Results 101 to 110 of about 184,630 (295)

Reliability and maintainability assessment factors for reliable fault-tolerant systems [PDF]

open access: yes, 1984
A long term goal of the NASA Langley Research Center is the development of a reliability assessment methodology of sufficient power to enable the credible comparison of the stochastic attributes of one ultrareliable system design against others.
Bavuso, S. J.
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Co-seismic deformation during the M_w 7.3 Aqaba earthquake (1995) from ERS-SAR interferometry [PDF]

open access: yes, 2000
The M_w 7.3 1995 Aqaba earthquake is the largest instrumental earthquake along the Dead Sea Fault. We complement previous seismological studies by analyzing co‐seismic ground displacement from differential interferometry computed from ERS images spanning
Avouac, Jean-Philippe   +2 more
core  

Stacco: Differentially Analyzing Side-Channel Traces for Detecting SSL/TLS Vulnerabilities in Secure Enclaves

open access: yes, 2017
Intel Software Guard Extension (SGX) offers software applications enclave to protect their confidentiality and integrity from malicious operating systems.
Almeida José Bacelar   +18 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Algebraic fault attack on PRESENT

open access: yesTongxin xuebao, 2012
A new fault analysis method on PRESENT—algebraic fault attack was proposed.This attack combined conventional algebraic cryptanalysis with fault attack,firstly built equivalent Boolean algebraic equations of cipher encryption by algebraic cryptanalysis ...
Ke-hui WU   +4 more
doaj   +2 more sources

Fault diagnosis of accelerometer servo circuit output saturation based on feature electrical parameters extraction

open access: yesHeliyon
The servo circuit of quartz flexible accelerometer is an extremely vital microelectronic device in inertial system. The paper introduces the traditional analysis process about output saturation fault of accelerometer servo circuit.
Ming Zhang   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Home - About - Disclaimer - Privacy