Results 71 to 80 of about 184,630 (295)

Analysis of the potential mechanisms of rockbursts [PDF]

, 2006
Sudden slip on geological faults or other discontinuities in rock may be preceded by an initial phase of "slow" fault creep. A simple plane strain model of a suddenly loaded fault is analysed to illustrate the possible transition from stable slip ...
Napier, J.A.L.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Analysis and Optimization of Differential Abnormal Noise Tests for Low Speed Steering

Jixie chuandong, 2022
Differential is one of the important parts of automobile transmission system. The analysis of its fault mode and the control of it have always been the focus in the automotive industry.
Jun Zhang, Yongzhong Bao, Shengxiang Chu, Hanfang Zhang   +3 more
doaj  

Fingerprinting stress: stylolite and calcite twinning paleopiezometry revealing the complexity of progressive stress patterns during folding-the case of the Monte Nero anticline in the Apennines, Italy [PDF]

, 2016
In this study we show for the first time how quantitative stress estimates can be derived by combining calcite twinning and stylolite roughness stress fingerprinting techniques in a fold-and-thrust belt.
Aharonov, Einat, Beaudoin, Nicolas, Billi, Andrea, Koehn, Daniel, Lacombe, Olivier, Lecouty, Alexandre, Parlangeau, Camille   +6 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Meta-heuristic algorithms in car engine design: a literature survey [PDF]

, 2015
Meta-heuristic algorithms are often inspired by natural phenomena, including the evolution of species in Darwinian natural selection theory, ant behaviors in biology, flock behaviors of some birds, and annealing in metallurgy.
Tayarani-N, Mohammad-H., Xu, Hongming, Yao, Xin   +2 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Pilot Differential Protection Scheme Based on Dominant Frequency Band for the Outgoing Lines of Inverter-Interfaced Renewable Energy Generator Station

IEEE Access
The reliability of conventional Pilot Differential Protection (PDP) may decrease when applied to outgoing lines that integrate Inverter-interfaced Renewable Energy Generator (IIREG) into the grid.
Changchang Yang, Yafang Tang, Jindai Wang, Ji Zhou, Yi Pu   +4 more
doaj   +1 more source

On the Selection of Calculable Residual Generators for UAV Fault Diagnosis

, 2016
Structural Analysis is an established method for Fault Detection and Identification (FDI) in large-scale systems, enabling the discovery of Analytical Redundancy Relations (ARRs) which serve as residual generators.
Kyriakopoulos, Kostas J., Zogopoulos-Papaliakos, Georgios   +1 more
core   +1 more source