Results 51 to 60 of about 178,711 (264)

Design and Evaluation of Digital Baseband Converter Sub-channel Delay Compensation Method on Bandwidth Synthesis [PDF]

Radioengineering, 2015
The effect of sub-channel delay on bandwidth synthesis is investigated to eliminate the “phase step” phenomenon in bandwidth synthesis during the test of CDBE (Chinese Digital Backend).
Kun Jiang, Pingbo Yan, Yuanqin Wang, Yiwen Jiao, Xin Lian, Ke Xu   +5 more
doaj  

Limitations on Hybrid WDM/OTDM Multicast Overlay System Imposed by Nonlinear Polarization Effect and its Mitigation

IEEE Photonics Journal, 2017
This paper investigates the nonlinear polarization effect of 120-Gbps polarization and subcarrier multiplexed unicast signal and 40-Gbps multicast signal on transmission performance of hybrid WDM/OTDM multicast overlay system.
Sukhbir Singh, Surinder Singh
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Optimal Design of High-Channel-Count Fiber Bragg Grating Filters With Low Index Modulation Using an Improved Differential Evolution Algorithm

IEEE Photonics Journal, 2013
An effective optimization method based on a self-adaptive differential evolution (DE) algorithm is proposed to design high-channel-count fiber Bragg grating (FBG) filters.
Jing Chen, Hao Jiang, Zengruan Ye, Xiaoli Fu, Jianjie Zhu, Tundong Liu   +5 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Patient and health care system delays in the start of tuberculosis treatment in Norway

BMC Infectious Diseases, 2006
Background Delay in start of tuberculosis (TB) treatment has an impact at both the individual level, by increasing the risk of morbidity and mortality, and at the community level, by increasing the risk of transmission.
Rygh Jens, Farah Mohamed, Steen Tore W, Selmer Randi, Heldal Einar, Bjune Gunnar   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of Fluticasone and Salmeterol on Tracheal Responsiveness to Ovalbumin and Lung Inflammation, Administrated during and after Sensitization

The Scientific World Journal, 2014
The effect of duration of administration of fluticasone propionate and salmeterol on tracheal responsiveness to ovalbumin and total and differential white blood cell in sensitized guinea pig was examined.
Zahra Gholamnezhad, Mohammad Hossain Boskabady, Mohammad Reza Khazdair, Mahmoud Hosseini, Mahdi Abbasnejad   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source