Results 111 to 120 of about 126,817 (263)
Uniqueness of solutions to a system of differential inclusions
Electronic Journal of Differential Equations, 2000 In this paper we study the uniqueness of solutions to the initial and Dirichlet boundary-value problem of differential inclusions $$ Delta u_i+ablacdotvec {B_i} (u_1,u_2,dots,u_N)in {partial F_i(u_i) over partial t}, quad i=1,2,dots,N, $$ where $vec{B_i}(
Chunpeng Wang, Jingxue Yin
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Electronic Journal of Differential Equations, 2014 In this article, we study a periodic second-order differential inclusions with locally Lipschitz potentials. By means of the least action principle and the minimax principle of nonsmooth type, we prove the existence of two nontrivial periodic ...
Lizhen Chen, Qinghua Zhang, Gang Li
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Second order tangency conditions and differential inclusions: a counterexample and a remedy
Electronic Journal of Differential Equations, 2009 In this paper we show that second order tangency conditions are superfluous not to say useless while discussing the existence condition for certain second order differential inclusions. In this regard, a counterexample is provided even in the simpler
Corneliu Ursescu
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Existence results for functional differential inclusions
Electronic Journal of Differential Equations, 2001 In this note we investigate the existence of solutions to functional differential inclusions on compact intervals. We use the fixed point theorem introduced by Covitz and Nadler for contraction multi-valued maps.
Mouffak Benchohra, Sotiris K. Ntouyas
doaj
BV Solutions to Evolution Inclusion with a Time and Space Dependent Maximal Monotone Operator
MathematicsThis paper deals with the research of solutions of bounded variation (BV) to evolution inclusion coupled with a time and state dependent maximal monotone operator. Different problems are studied: existence of solutions, unicity of the solution, existence
Charles Castaing +2 more
doaj +1 more source
, 2013 We study the time optimal control problem with a general target $\mathcal S$ for a class of differential inclusions that satisfy mild smoothness and controllability assumptions.
Cannarsa, Piermarco +2 more
core +1 more source