Results 101 to 110 of about 47,664 (300)

Towards controlled Fizeau observations with the Large Binocular Telescope

open access: yes, 2018
The Large Binocular Telescope Interferometer (LBTI) can perform Fizeau interferometry in the focal plane, which accesses spatial information out to the LBT's full 22.7-m edge-to-edge baseline.
Defrere   +10 more
core   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

open access: yesAdvanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li   +6 more
wiley   +1 more source

The Use of C-/X-Band Time-Gapped SAR Data and Geotechnical Models for the Study of Shanghai’s Ocean-Reclaimed Lands through the SBAS-DInSAR Technique

open access: yesRemote Sensing, 2016
In this work, we investigate the temporal evolution of ground deformation affecting the ocean-reclaimed lands of the Shanghai (China) megacity, from 2007 to 2016, by applying the Differential Synthetic Aperture Radar Interferometry (DInSAR) technique ...
Antonio Pepe   +4 more
doaj   +1 more source

Quantum test of the equivalence principle for atoms in superpositions of internal energy eigenstates

open access: yes, 2017
The Einstein Equivalence Principle (EEP) has a central role in the understanding of gravity and space-time. In its weak form, or Weak Equivalence Principle (WEP), it directly implies equivalence between inertial and gravitational mass.
Brukner, C.   +7 more
core   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

open access: yesAdvanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang   +12 more
wiley   +1 more source

Double-Fock superposition interferometry for differential diagnosis of decoherence

open access: yesNew Journal of Physics, 2015
Interferometric signals are degraded by decoherence, which encompasses dephasing, mixing and any distinguishing which-path information. These three paradigmatic processes are fundamentally different, but, for coherent, single-photon and $N00N$ -states ...
Malte C Tichy   +5 more
doaj   +1 more source

Interpretation of Aerial Photographs and Satellite SAR Interferometry for the Inventory of Landslides

open access: yesRemote Sensing, 2013
An inventory of landslides with an indication of the state of activity is necessary in order to establish hazard maps. We combine interpretation of aerial photographs and information on surface displacement from satellite Synthetic Aperture Radar (SAR ...
Christian Ambrosi   +2 more
doaj   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

open access: yesAdvanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji   +10 more
wiley   +1 more source

Why Chromatic Imaging Matters

open access: yes, 2018
During the last two decades, the first generation of beam combiners at the Very Large Telescope Interferometer has proved the importance of optical interferometry for high-angular resolution astrophysical studies in the near- and mid-infrared.
Baron, Fabien   +17 more
core   +3 more sources

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy   +8 more
wiley   +1 more source

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