Results 151 to 160 of about 230,628 (307)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Rasch analysis of the self efficacy (SE-12) questionnaire measuring clinical communication skills

open access: yesPEC Innovation
Objective: The aim of this study was to examine the construct validity and reliability of the Self Efficacy (SE-12) questionnaire using Rasch analysis. Methods: The SE-12 was administered to Danish health care professionals prior to their participation ...
Kaj Sparle Christensen, Jette Ammentorp
doaj   +1 more source

Validity of a visual impairment questionnaire in measuring cataract surgery outcomes [post print] [PDF]

open access: yes, 2008
PURPOSE: To test the validity of the Impact of Visual Impairment (IVI) questionnaire in a cataract population. SETTING: Flinders Eye Centre, Flinders Medical Centre, Flinders University, Adelaide, South Australia.
Caudle, Lynda Elisabeth   +3 more
core  

Does Functional Somatic Symptoms measurement differ across Sex and Age? Differential Item Functioning in Somatic Symptoms measured with the CIDI

open access: gold, 2021
Angélica Acevedo-Mesa   +5 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Differential Item Functioning of the Psychological Domain of the Menopause Rating Scale [PDF]

open access: hybrid, 2016
Álvaro Monterrosa‐Castro   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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