Results 161 to 170 of about 48,174 (313)

Differential item functioning of the Geriatric Depression Scale-short form in the NACC dataset. [PDF]

Alzheimers Dement
Renn BN, Cross CL, Zaman I, Singsank KT, Cobos K, John SE.   +5 more
europepmc   +1 more source

Comparison of machine learning methods with an underlying logistic regression model to detect differential item functioning in patient-reported outcome measures

Background: Patient-reported outcome measures (PROMs) are self-report instruments about health-related quality of life and well-being (i.e., physical and mental health).
Dorostimotlagh, Razieh
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

DIFFERENTIAL ITEM FUNCTIONING PADA TES MULTIDIMENSI

, 2014
The presence of differential item functioning (DIF) to an item assumed unidimensional often attributed to the assumption of multidimensionality. Therefore, itâ s interested to prove whether multidimensionality elicited items to be DIF between focal and ...
, ALI RIDHO, , Prof. Dr. Saifuddin Azwar, MA, , Prof. Djemari Mardapi, Ph.D   +2 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Reducing Differential Item Functioning via Process Data. [PDF]

Psychometrika
Chen L, Zhang S, Liu J.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Estimating Trends With Differential Item Functioning: A Comparison of Five IRT-Based Approaches. [PDF]

Educ Psychol Meas
Engels O, Lüdtke O, Robitzsch A.
europepmc   +1 more source

Differential item functioning methods as an item bias indicator

, 2012
Differential item functioning is an approach that is widely used to find out items that are bias. This study investigated items that are bias using differential item functioning approach in relation to school type (private and public schools) school ...
Ogbebor, U., Onuka, A. O. U.
core