Results 201 to 210 of about 43,361 (264)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Using moderated nonlinear factor models to adjust for differential item functioning in the Student-Teacher Relationship Scale from kindergarten to Grade 6. [PDF]

J Sch Psychol
Magro SW, DeJoseph ML, Pianta RC, Roisman GI.   +3 more
europepmc   +1 more source

Sex-related differential item functioning of the Jenkins Sleep Scale: a cross-sectional study among 77 967 employees in the Finnish public sector. [PDF]

BMJ Open
Juhola J, Arokoski JPA, Ervasti J, Kivimäki M, Vahtera J, Myllyntausta S, Saltychev M.   +6 more
europepmc   +1 more source

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Differential Item Function

2016
For every IRT model, a mathematical function is used to specify the probability of item responses as a function of the ability (latent trait). The degree to which the observed data fit the mathematical function needs to be examined since valid results can only be drawn if the data fit the model.
Margaret Wu, Hak Ping Tam, Tsung-Hau Jen
openaire   +1 more source

Estimating the Importance of Differential Item Functioning

Journal of Educational and Behavioral Statistics, 1995
Several methods have been proposed to detect differential item functioning (DIF), an item response pattern in which members of different demographic groups have different conditional probabilities of answering a test item correctly, given the same level of ability. In this article, the mixture index of fit, proposed by Rudas, Clogg, and Lindsay (1994) ,
Tamás Rudas, Rebecca Zwick
openaire   +1 more source

Differential item functioning and health assessment

Quality of Life Research, 2007
Establishing measurement equivalence is important because inaccurate assessment may lead to incorrect estimates of effects in research, and to suboptimal decisions at the individual, clinical level. Examination of differential item functioning (DIF) is a method for studying measurement equivalence.
Jeanne A, Teresi, John A, Fleishman
openaire   +2 more sources