Results 61 to 70 of about 311,948 (264)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

On the Rank of Multigraded Differential Modules

open access: yesMichigan Mathematical Journal
A $\mathbb{Z}^d$-graded differential $R$-module is a $\mathbb{Z}^d$-graded $R$-module $D$ equipped with an endomorphism, $δ$, that squares to zero. For $R=k[x_1,\ldots,x_d]$, this paper establishes a lower bound on the rank of such a differential module when the underlying R-module is free. We define the Betti number of a differential module and use it
Boocher, Adam, Devries, Justin W.
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Grand Minima in a spherical non-kinematic α2Ω mean-field dynamo model

open access: yesJournal of Space Weather and Space Climate, 2020
We present a non-kinematic axisymetric α2Ω mean-field dynamo model in which the complete α-tensor and mean differential rotation profile are both extracted from a global magnetohydrodynamical simulation of solar convection producing cycling large-scale ...
Simard Corinne, Charbonneau Paul
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Flexible Common-Mode Voltage Modulation Strategy for Differential Boost Inverters

open access: yesEnergies
Photovoltaic power generation and energy storage technology are current hotspots in the clean energy industry. As a core piece of equipment, an inverter is subjected to higher demands for its voltage regulation range and output performance.
Zhaozhe Deng   +5 more
doaj   +1 more source

Differential modules and K-groups

open access: yesJournal of Algebra, 1991
Having defined dlog and res maps, the author proves that the following diagram of abelian sheaves on \(X\) is commutative for all \(p>0\) with exact rows, where \(X\) is a smooth scheme over a field of characteristic 0, \(Y\) is closed subscheme of codimension one in \(X\), \(U=X-Y\), and the top row is the localization sequence of \(K\)-sheaves ...
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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