Results 121 to 130 of about 3,726,319 (376)

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

STARLIKENESS OF q DIFFERENTIAL OPERATOR INVOLVING QUANTUM CALCULUS

open access: yes, 2014
In the present paper, we investigate starlikeness condi- tions for $ q$ − differential operator by using the concept of quantum calculus in the unit disk.
I. Aldawish, M. Darus
semanticscholar   +1 more source

Operator Differentiable Functions

open access: yesPublications of the Research Institute for Mathematical Sciences, 2000
We study the Banach {}^* -algebra C^1_{\mathrm{op}}(I) of C^1 -functions on the compact interval I such that the corresponding ...
openaire   +2 more sources

On the best approximation of the differentiation operator [PDF]

open access: yesUral mathematical journal, 2015
In this paper we give a solution of the problem of the best approximation in the uniform norm of the differentiation operator of order k by bounded linear operators in the class of functions with the property that the Fourier transforms of their derivatives of order n (0 < k
openaire   +3 more sources

Local spectral radius formulas for a class of unbounded operators on Banach spaces

open access: yes, 2011
We exhibit a general class of unbounded operators in Banach spaces which can be shown to have the single-valued extension property, and for which the local spectrum at suitable points can be determined. We show that a local spectral radius formula holds,
Andersen, Nils Byrial, de Jeu, Marcel
core  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Analytical and qualitative investigation of COVID-19 mathematical model under fractional differential operator. [PDF]

open access: yesMath Methods Appl Sci, 2021
Shah K   +5 more
europepmc   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Neutral Operator and Neutral Differential Equation

open access: yesAbstract and Applied Analysis, 2011
In this paper, we discuss the properties of the neutral operator (Ax)(t)=x(t)−cx(t−δ(t)), and by applying coincidence degree theory and fixed point index theory, we obtain sufficient conditions for the existence, multiplicity, and nonexistence of ...
Jingli Ren, Zhibo Cheng, Stefan Siegmund
doaj   +1 more source

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