Results 51 to 60 of about 56,445 (299)

Limiting Privacy Breaches in Differential Privacy

open access: yesAdvances in Intelligent Systems Research, 2014
In recently years, privacy-preserving data mining has become more import and attractedmore attention from data mining community. Among the existing privacy preserving models, -differential privacy provides the strongest privacy guarantees and has no assumption about the adversary's background information and compute ability.
Liu Shaopeng, Yin Jian, Ouyang Jia
openaire   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Randomized Privacy Budget Differential Privacy

open access: yes, 2022
arXiv admin note: text overlap with arXiv:2009 ...
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

MPDP -medoids: Multiple partition differential privacy preserving -medoids clustering for data publishing in the Internet of Medical Things

open access: yesInternational Journal of Distributed Sensor Networks, 2021
The tremendous growth of Internet of Medical Things has led to a surge in medical user data, and medical data publishing can provide users with numerous services. However, neglectfully publishing the data may lead to severe leakage of user’s privacy.
Zekun Zhang   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Child Health Dataset Publishing and Mining Based on Differential Privacy Preservation

open access: yesMathematics
With the emergence and development of application requirements such as data analysis and publishing, it is particularly important to use differential privacy protection technology to provide more reliable, secure, and compliant datasets for research in ...
Wenyu Li   +3 more
doaj   +1 more source

Smoothed Differential Privacy

open access: yes, 2021
Differential privacy (DP) is a widely-accepted and widely-applied notion of privacy based on worst-case analysis. Often, DP classifies most mechanisms without external noise as non-private [Dwork et al., 2014], and external noises, such as Gaussian noise or Laplacian noise [Dwork et al., 2006], are introduced to improve privacy.
Liu, Ao, Wang, Yu-Xiang, Xia, Lirong
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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