The present study aimed to evaluate analytical performances of radial immunodiffusion (RID) technique for the quantification of milk lactoferrin (LF), and to investigate the main sources of variation of LF concentration in individual milk samples of ...
Giovanni Niero+6 more
doaj +1 more source
The study evaluated the dynamics of macrophages and polymorphonuclear leukocytes milk-secreted by Mediterranean Buffaloes (MBs). Sixty quarter-milk-samples were collected and divided into three groups (n = 20 units each one): clinical mastitis (CM ...
Maria Chiara Alterisio+2 more
doaj +1 more source
Dynamics of single human embryonic stem cells and their pairs: a quantitative analysis [PDF]
Numerous biological approaches are available to characterise the mechanisms which govern the formation of human embryonic stem cell (hESC) colonies. To understand how the kinematics of single and pairs of hESCs impact colony formation, we study their mobility characteristics using time-lapse imaging.
arxiv +1 more source
MicroRNA regulation of bovine monocyte inflammatory and metabolic networks in an in vivo infection model. [PDF]
peer-reviewedBovine mastitis is an inflammation-driven disease of the bovine mammary gland that costs the global dairy industry several billion dollars per annum.
Baker, Mike+10 more
core +1 more source
The somatic cell count in cow's milk is used to control the inflammatory infection process and to assess the likelihood of subclinical and clinical mastitis.
A. Sermyagin
semanticscholar +1 more source
Hierarchical tissue organization as a general mechanism to limit the accumulation of somatic mutations [PDF]
How can tissues generate large numbers of cells, yet keep the divisional load (the number of divisions along cell lineages) low in order to curtail the accumulation of somatic mutations and reduce the risk of cancer? To answer the question we consider a general model of hierarchically organized self-renewing tissues and show that the lifetime ...
arxiv +1 more source
Cell Division, Differentiation and Dynamic Clustering [PDF]
A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to show three successive stages with the growth of the number of cells; coherent growth, dynamic clustering, and fixed ...
arxiv +1 more source
Local host response following an intramammary challenge with Staphylococcus fleurettii and different strains of Staphylococcus chromogenes in dairy heifers [PDF]
Coagulase-negative staphylococci (CNS) are a common cause of subclinical mastitis in dairy cattle. The CNS inhabit various ecological habitats, ranging between the environment and the host.
A Harada+47 more
core +5 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
The Biophysical Micro-Environment's Influence on Cell Fate Decisions During Macrophage Activation and Somatic Cell Reprogramming [PDF]
Cells are known to sense and respond to their mechanical microenvironment in profound ways. Various evidence has implicated the adhesome, a body of adhesion associated proteins, in several cell fate decisions, including differentiation and proliferation.
arxiv