Results 71 to 80 of about 30,448 (236)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Blood neutrophil extracellular traps: a novel target for the assessment of mammary health in transition dairy cows

open access: yesJournal of Animal Science and Biotechnology, 2022
Background Mammary health is important for transition dairy cows and has been well recognized to exert decisive effects on animal welfare. However, the factors influencing mammary health are still unclear.
Luyi Jiang   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Cut-off values and genetic aspects of differential somatic cell count in dairy cows

open access: yes, 2019
The knowledge of the proportion of the different cell types in milk, rather than just the overall somatic cell count (SCC), could provide valuable information for a more precise definition of the health status of the udder.
Ali Zidi   +3 more
core   +1 more source

Cell population, viability, and some key immunomodulatory molecules in different milk somatic cell samples in dairy cows [PDF]

open access: yes, 2009
Immune cells in the milk are most important in combating pathogens that invade the mammary gland. This study investigated the immune competence and viability of somatic milk cells that are already resident in milk and udders free of infection. Cells were
Wellnitz, O.   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The rheology of gel formed during the California Mastitis Test

open access: yes, 2006
One of the most costly diseases in the dairy industry is mastitis, which is an inflammation of the mammary gland. Mastitis influences the quality of milk and therefore reduces financial returns to both the farmer and the processor.
Xia, Sen
core  

Impact of slaughter on the reliability of somatic cell count (SCC) and differential milk cell count (DMCC) as diagnostic markers in milk

open access: yesJournal of Dairy Research
Abstract This research paper addresses the hypothesis that the in vivo criterion of bovine somatic cell count (SCC) < 200,000 cells/ml milk as a diagnostic marker for healthy mammary tissue is not suitable to be adopted to milk samples taken post ...
Lisa Oberberger   +6 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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