Results 71 to 80 of about 507,215 (264)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Design and Characterization of Low‐Threshold InP Nanowire Photonic Crystal Surface‐Emitting Lasers
Advanced Photonics ResearchThis study examines the lasing performance of optically pumped wurtzite‐phase InP nanowire (NW) photonic crystal surface‐emitting lasers (PCSELs) with the goal of optimizing the cavity design for low‐threshold lasing.
Navoda Jayawardana +8 more
doaj +1 more source
Differential visual depth threshold of the chick [PDF]
Psychonomic Science, 1968 The differential visual depth threshold of the chick was tested on the visual cliff. The chicks chose the shallow side reliably when the deep side was 2 in. or more below the shallow side. At 1–3/4 in., 1–1/2 in. or 1 in. visual distance of the deep side below the glass, the shallow side was chosen at a chance level.
Richard D. Walk +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Doppler differential value weighted cycle slip detection and recovery [PDF]
AIP AdvancesThe present paper proposes a Doppler differential value-weighted real-time BDS cycle slip detection method. This approach represents a novel utilization of Doppler values for the detection of cycle slip.
Chenglin Xie +3 more
doaj +1 more source
A Differential Threshold of Breakfast, Caffeine and Food Groups May Be Impacting Mental Well-Being in Young Adults: The Mediation Effect of Exercise. [PDF]
Front Nutr, 2021 Begdache L +4 more
europepmc +1 more source