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Gene Expression during Vascular Pericyte Differentiation
Critical Reviews in Eukaryotic Gene Expression, 1999Pericytes, an integral part of the microvasculature, are involved in a number of different processes, including angiogenesis. Many of the early studies on these cells are descriptive and concentrate on the location of pericytes in vivo, surrounding the endothelial cells in the microvessels.
Doherty, Mary Jo, Canfield, Ann E.
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From differential gene expression to differential gene function and back
Drug Discovery Today: Technologies, 2004Following the decoding of several plant and animal genomes, the identification of all corresponding transcripts and proteins and understanding how their expression corresponds to physiological and pathological states is the obvious next step. Nucleic acid quantification methods have become increasingly high-throughput and relatively low-cost, and ...
Moitreyee, Chatterjee-Kishore +1 more
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Journal of Trace Elements in Medicine and Biology, 2018
BACKGROUND Kashin-Beck disease (KBD) is a childhood-onset endemic osteoarthropathy in China. Nutrients including trace elements may play active roles in the development of KBD.
Y. Ning +9 more
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BACKGROUND Kashin-Beck disease (KBD) is a childhood-onset endemic osteoarthropathy in China. Nutrients including trace elements may play active roles in the development of KBD.
Y. Ning +9 more
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Amplified Differential Gene Expression Microarray
2004Amplified Differential Gene Expression (ADGE) and DNA microarray provides a new concept that the ratios of differentially expressed genes are magnified prior to detecting them. The ratio magnification is achieved with the integration of DNA reassociation and polymerase chain reaction (PCR) amplification and ensured with the design of the adapters and ...
Zhijian J, Chen, Kenneth D, Tew
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Finding differentially expressed genes
Proceedings of the 2004 ACM symposium on Applied computing, 2004In this paper, we consider finding differentially expressed genes in a dataset of microarray experiments for pattern generation. We developed two methods which are mainly based on the q-values approach; the first is a direct extension of the q-values approach, while the second uses two approaches: q-values and maximum-likelihood.
Osman Abul +3 more
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Visualizing differentially expressed genes
SPIE Proceedings, 2006Identification of significantly differentially expressed genes (marker genes) among sample groups is a central issue in microarray analysis. This identification is important to understand the molecular pathway of diseases. Many statistical methods have been proposed to locate marker genes. These methods depend on a cutoff value for selection.
Atiq U. Islam +2 more
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Mesothelial Differentiation as Reflected by Differential Gene Expression
American Journal of Respiratory Cell and Molecular Biology, 2004Human mesothelial cells obtained from benign effusions retain their proliferative capacity and grow uniformly either with a fibroblastic or epithelioid morphology in vitro. These cultures therefore provide a model for the process of mesothelial differentiation in vivo.
Xiaojuan, Sun +2 more
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Genes differentially expressed in prostate cancer
BJU International, 2004Because of the heterogeneity of prostate cancer knowledge about the genes involved in prostate carcinogenesis is still very limited. Previously, the use of novel high‐throughput technologies offered the possibility to investigate broad gene expression profiles and thus helped to improve understanding of the molecular basis of prostate disease.
I E, Eder +4 more
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Analysing differential gene expression in cancer
Nature Reviews Cancer, 2003Analysis of messenger RNA and proteins is widely used to compare patterns of gene expression between cells or tissues of different kinds and under different conditions; for example, between normal and cancer cells. The goal of the individuals who are developing these methods has been to enable faster, simpler, more sensitive and systematic analyses ...
Peng, Liang, Arthur B, Pardee
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POGIL Activity Clearinghouse
The trillions of cells in the human body can be categorized into hundreds of specialized cell types. All of these cells arise from the original fertilized egg and contain the same DNA. Differences among the cell types arise because cells selectively express some genes but not others.
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The trillions of cells in the human body can be categorized into hundreds of specialized cell types. All of these cells arise from the original fertilized egg and contain the same DNA. Differences among the cell types arise because cells selectively express some genes but not others.
openaire +1 more source