Results 101 to 110 of about 901,448 (288)

Differentiated Instruction in the Elementary Classroom [PDF]

open access: yes, 2022
The purpose of this study is to analyze differentiated instruction in the elementary classroom and ways teachers are able to see if their instruction is effective. The goal of this studyis to consider, "What is differentiated instruction in an elementary
RaeAnne Sanchez
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Primary School Students’ Perspectives on Differentiated Instruction Supported by Digital Tools

open access: yes
The concept of differentiated instruction is frequently discussed as a potential strategy for creating inclusive classrooms and promoting equity in education. Yet relatively little is known about students’ perceptions of these educational settings.
Oberholzer, Franziska, Zahnd, Raphael
core  

Differentiated instruction in context: Insights from school leaders and teachers in a rural Australian Catholic primary school

open access: yes
Differentiated instruction has emerged as an effective teaching pedagogy, one well suited in today's classrooms where teachers are required to meet the academic needs of every learner. While research on differentiated instruction in Australia is growing,
Webster, Grant, Gibbs, Kathryn
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

AI-ASSISTED DIFFERENTIATED INSTRUCTION AND EFL WRITING MOTIVATION: A CORRELATIONAL STUDY

open access: yesArmenian Folia Anglistika
The integration of artificial intelligence (AI) for learning personalization has emerged as an approach to address diverse learner needs. This quantitative correlational study examined the relationship between the perceived value of AI-assisted ...
Bouchra Si-Mohammed, Souhila Hellalet
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

KEBERAGAMAN PESERTA DIDIK DAN PERAN PEMBELAJARAN BERDIFERENSIASI DALAM PEMENUHAN TARGET KURIKULUM

open access: yesGuruku
In the 21st century, education demands a transition from teacher-centered to student-centered methodologies. This shift is essential for equipping students with key 21st-century competencies, commonly known as the 4Cs (Communication, Collaboration ...
Moh. Nafis Husen Romadani   +1 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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