Results 81 to 90 of about 901,448 (288)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

One Size Does Not Fit All: Understanding Differentiated Instruction in Elementary Mixed-Ability Classrooms

, 2017
Differentiated instruction (DI) serves as an umbrella term for various approaches that educators adopt to ensure that students can access the curriculum through multiple avenues, ultimately achieving the vision of equitable classrooms across educational ...
Avgousti, Melbo
core  

Effects of Differentiated Instruction on Students' Empowered Learning Skills

Education policymakers and teachers’ roles are vital in providing an environment that empowers learners. In a classroom, each learner has different learning profiles and in such an environment, a one-size-fits-all teaching method is ineffective.
Titus, Anto
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Differentiated instruction : does it work? [PDF]

, 2003
The fact that every child is unique poses a dilemma for educators. The model for differentiated instruction requires teachers to be flexible in their approach to adjusting the curriculum and presentation of information to learners.
Maher, Michelle
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

DIFFERENTIATED INSTRUCTION FOR EFL CLASSROOM

, 2021
Because each student is unique, the diversity in their ways of learning and speed of learning needs to be considered to help them achieve the best process and outcome.
Suwastini, Ni Komang Arie, Dantes, Gede Rasben, Jayantini, I Gusti Agung Sri Rwa, Rinawati, Ni Kadek Ayu   +3 more
core   +1 more source

Investigating differentiated instruction and the contributing factors to cater EFL students’ needs at the collegial level

Asian-Pacific Journal of Second and Foreign Language Education
Teaching language has challenges for many reasons, including learners’ backgrounds, learning styles, motivation, and socio-economic status. However, EFL students can benefit from differentiation across the learning continuum to a large extent. This study
Omid Tajik, Shagofah Noor, Jawad Golzar
doaj   +1 more source

Developing EFL Writing Skills and Self-Regulation Using Blended Differentiated Instruction among Fourth Grade Primary Stage Pupils [PDF]

Maǧallaẗ Kulliyyaẗ Al-Tarbiyyaẗ Bi-Dumyāṭ
The present research aimed at investigating the effect of using Blended Differentiated Instruction on developing EFL writing skills and Self-regulation among fourth grade primary stage pupils.
Mohamed Ahmed Sayed Ahmed Sayed Ahmed Dawoud, Heba Moustafa Elmansi, Aly Abdul-Samea Qoura   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source