Results 61 to 70 of about 602,927 (312)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Analysis of uniform binary subdivision schemes for curve design [PDF]

open access: yes, 1988
The paper analyses the convergence of sequences of control polygons produced by a binary subdivision scheme of the form .0,1,2,...kz,ikj,ifjbm0j1k12ifjam0j1k2if=∈+Σ==++Σ==+ The convergence of the control polygons to a Cu curve is analysed in terms of ...
Dyn, N, Gregory, JA, Levin, D
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Vertical integration, market foreclosure and quality investment [PDF]

open access: yes, 2006
Incentives to vertically integrate are studied in an industry where downstream firms are vertically differentiated. Vertical integration by one of the firms increases production costs for the rival.
Hernán, Roberto, Kujal, Praveen
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Nordic Administrative Collaboration: Scope, Predictors and Effects on Policy Design and Administrative Reform Measures

open access: yesPolitics and Governance, 2020
This article examines whether Nordic administrative collaboration is still ‘alive and kicking,’ or whether it has been marginalized by increased integration into Europe and strong international reform trajectories.
Per Lægreid, Lise H. Rykkja
doaj   +1 more source

Changes in Intra-industry Competitiveness of the New Member States (EU-10) Economies During the Crisis, the Years 2009-2011 [PDF]

open access: yes, 2013
This paper aims to present the main results of our analysis of changes in the trade flows of the examined countries in the initial years after the accession (2003-2008), and subsequently during the crisis (2009-2011).
Molendowski, Edward, Polan, Wojciech
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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