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Prognostic value of somatic mutation testing and different methods of treatment of low-risk differentiated thyroid cancer [PDF]

open access: yesЭндокринная хирургия, 2019
Background: Using molecular testing for prediction the course of the disease could possibly help doctors in making therapeutic decisions about the management of patients, because it remains controversial issues in low-risk differentiated thyroid cancer ...
Vera A. Kachko   +2 more
doaj   +1 more source

Retrospective analysis of clinical characteristics and risk factors of differentiated thyroid cancer in children

open access: yesFrontiers in Pediatrics, 2022
BackgroundThe incidence rate of children with thyroid cancer has an increasing trend. This study aimed to investigate the clinical characteristics and therapeutic approaches of differentiated thyroid cancer (DTC) in Chinese children.Materials and ...
Chun Chen   +21 more
doaj   +1 more source

Recent Improvements in Genomic and Transcriptomic Understanding of Anaplastic and Poorly Differentiated Thyroid Cancers [PDF]

open access: yesEndocrinology and Metabolism, 2020
Anaplastic thyroid cancer (ATC) is a lethal human cancer with a 5-year survival rate of less than 10%. Recently, its genomic and transcriptomic characteristics have been extensively elucidated over 5 years owing to advance in high throughput sequencing ...
Seong-Keun Yoo   +3 more
doaj   +1 more source

Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) may be superior to C-reactive protein (CRP) for predicting the occurrence of differentiated thyroid cancer

open access: yesEndocrine Regulations, 2017
Objectives. NLR (neutrophil-lymphocyte ratio) and PLR (platelet-lymphocyte ratio) are prognostic markers of differentiated thyroid cancers. In our study, we evaluated NLR, PLR and C-reactive protein (CRP) for predicting the occurence of differentiated ...
Ozmen S   +7 more
doaj   +1 more source

Significance of telomerase reverse-transcriptase promoter mutations in differentiated thyroid cancer

open access: yesFormosan Journal of Surgery, 2021
Background: Telomerase reverse-transcriptase (TERT) encodes the reverse transcriptase of telomerase, and TERT promoter mutations are enriched in advanced thyroid cancer.
Hung-Fei Lai   +2 more
doaj   +1 more source

Well-differentiated thyroid cancer disclosed during pregnancy. Management experience

open access: yesЭндокринная хирургия, 2015
Thyroid cancer have the second place as malignancy detectable during pregnancy. Disclose of thyroid cancer during pregnancy raises many questions among endocrinologists, oncologists and obstetricians.
A. A. Ilyin   +8 more
doaj   +1 more source

A novel risk stratification model based on tumor size and multifocality to predict recurrence in pediatric PTC: comparison with adult PTC

open access: yesFrontiers in Endocrinology
BackgroundPediatric papillary thyroid cancer presents with a more advanced stage of disease than adult PTC; and it is more likely to be aggresive and distant metastases, although the survival rate is high.MethodsA retrospective observational study was ...
Rui Du   +13 more
doaj   +1 more source

The Role of Genetic Polymorphisms in Differentiated Thyroid Cancer: A 2023 Update

open access: yesBiomedicines, 2023
Thyroid cancer is the most common endocrine malignancy, with an increasing trend in the past decades. It has a variety of different histological subtypes, the most frequent one being differentiated thyroid cancer, which refers to papillary carcinoma, the
Robert Aurelian Tiucă   +2 more
doaj   +1 more source

The genomic and evolutionary landscapes of anaplastic thyroid carcinoma

open access: yesCell Reports
Summary: Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are unknown.
Peter Y.F. Zeng   +68 more
doaj   +1 more source

Actualities in Genetics of Differentiated Thyroid Cancer [PDF]

open access: yesActa Endocrinologica (Bucharest), 2020
Genetics of cancer is a hot topic, an excellent example of translational medicine. Risk stratification, selection of cases for surgery in Bethesda categories 3 &4 FNAB are examples of the high impact of genetic evaluation in thyroid neoplasia.
R, Dobrescu, C, Badiu
openaire   +2 more sources

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