Results 11 to 20 of about 3,508,804 (299)

Immunohistochemistry and next-generation sequencing for NTRK fusion detection in differentiated thyroid cancer of children, adolescents and young adults

Brazilian Journal of Oncology
Introduction: Pan-TRK immunohistochemistry staining can assess the protein expression from NTRK gene fusions. A little is known about its utility in differentiated thyroid cancer samples from children, adolescents, and young adults patients.
Ana Clara Oliveira Tosta Telles, Gabriel Jeferson Rodríguez Machado, Juliana Lima von-Ammon, Rafael Reis Campos da-Matta, Taíse Lima Cerqueira de-Oliveira, Fabyan Esberard de Lima Beltrão, Alexandre Rolim da-Paz, Fabio Hecht, Guilherme de Castro Lopes, Leonardo Freitas Boaventura Rios, Bruno da Silva Lisboa, Helton Estrela Ramos   +11 more
doaj   +2 more sources

Epigenetic Modifications: Novel Therapeutic Approach for Thyroid Cancer [PDF]

Endocrinology and Metabolism, 2017
The incidence of thyroid cancer is growing the fastest among all cancers in the United States, especially in women. The number of patients with thyroid neoplasm is part of an even larger number of patients who often need to undergo an operation to ...
Xuguang Zhu, Sheue-yann Cheng
doaj   +1 more source

Molecular Pathogenesis and Targeted Therapies in Well-Differentiated Thyroid Carcinoma [PDF]

Endocrinology and Metabolism, 2014
Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-γ, may carry diagnostic and prognostic ...
Jung Guk Kim
doaj   +1 more source

Association between hashimoto thyroiditis and differentiated thyroid cancer: A single-center experience

Frontiers in Oncology, 2022
Hashimoto’s thyroiditis is the most common cause of hypothyroidism in the iodine-sufficient areas of the world. Differentiated thyroid cancer is the most common thyroid cancer subtype, accounting for more than 95% of cases, and it is considered a tumor ...
Federico Cappellacci, Gian Luigi Canu, Maria Letizia Lai, Eleonora Lori, Miriam Biancu, Francesco Boi, Fabio Medas   +6 more
doaj   +1 more source

Actions of Thyroid Hormones on Thyroid Cancers

Frontiers in Endocrinology, 2021
L-Thyroxine (T4) is the principal ligand of the thyroid hormone analogue receptor on the extracellular domain of integrin αvβ3. The integrin is overexpressed and activated in cancer cells, rapidly dividing endothelial cells, and platelets.
Shaker A. Mousa, Aleck Hercbergs, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Kelly A. Keating, Paul J. Davis, Paul J. Davis   +8 more
doaj   +1 more source

External radiotherapy of thyroid cancer [PDF]

, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Pollinger, B., Dühmke, Eckhart
core   +1 more source

Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer

Эндокринная хирургия, 2015
The project of Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer is dedicated to the management of patients with differentiated thyroid cancer. The guideline modifications 2016 include the following matters:
Dmitriy Germanovich Bel'tsevich, Vladimir Eduardovich Vanushko, Galina Afanas'evna Mel'nichenko, Ali Muradovich Mudunov, Pavel Olegovich Rumyantsev, Il'ya Valer'evich Sleptsov   +5 more
doaj   +1 more source

Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer [PDF]

, 2009
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the publication of the American Thyroid Association's guidelines for the management of these disorders was published in
Steward DL, Tuttle RM, Schlumberger M, Martin Schlumberger, Stephanie L. Lee, Haugen, Bryan R., McIver B, Cooper, David S., Haugen BR, Cooper DS, American Thyroid Association Guidelines Taskforce on Thyroid Nodules, Mandel, Susan J., Steward, David L., Bryan McIver, Richard T. Kloos, Mazzaferri EL, Steven I. Sherman, Doherty, Gerard M., Sherman, Steven I., Susan J. Mandel, Lee SL, Kloos RT, R. Michael Tuttle, McIver, Bryan, Ernest L. Mazzaferri, Kloos, Richard T., Lee, Stephanie L., Gerard M. Doherty, Pacini, Furio, Doherty GM, Bryan R. Haugen, Schlumberger, Martin, Furio Pacini, Differentiated Thyroid Cancer, David S. Cooper, Mazzaferri, Ernest L., Mandel SJ, Sherman SI, David L. Steward, Tuttle, R. Michael   +39 more
core   +1 more source

Downregulation of miR-146b-3p Inhibits Proliferation and Migration and Modulates the Expression and Location of Sodium/Iodide Symporter in Dedifferentiated Thyroid Cancer by Potentially Targeting MUC20

Frontiers in Oncology, 2021
The dedifferentiation of differentiated thyroid cancer (DTC) is a challenging problem for radioactive iodine (131I) treatment, also known as radioiodine refractory differentiated thyroid cancer (RAIR-DTC). The purpose of this study was to further explore
Shasha Hou, Xiaorui Xie, Jing Zhao, Cailan Wu, Ning Li, Zhaowei Meng, Chunquan Cai, Jian Tan   +7 more
doaj   +1 more source

2017 Russian clinical practice guidelines for differentiated thyroid cancer diagnosis and treatment

Эндокринная хирургия, 2017
The Russian clinical practice guidelines for diagnosis and treatment of differentiated thyroid cancer is dedicated to the management of patients with differentiated thyroid cancer.
Dmitriy G. Beltsevich, Vladimir E. Vanushko, Pavel O. Rumiantsev, Galina A. Melnichenko, Nikolay S. Kuznetsov, Aleksandr Yu. Abrosimov, Vladimir G. Polyakov, Ali M. Mudunov, Sergey O. Podvyaznikov, Ilja S. Romanov, Andrey P. Polyakov, Ilja V. Sleptsov, Roman A. Chernikov, Sergey L. Vorobyov, Valentin V. Fadeyev   +14 more
doaj   +1 more source