The Role of Genetic Polymorphisms in Differentiated Thyroid Cancer: A 2023 Update
Thyroid cancer is the most common endocrine malignancy, with an increasing trend in the past decades. It has a variety of different histological subtypes, the most frequent one being differentiated thyroid cancer, which refers to papillary carcinoma, the
Robert Aurelian Tiucă +2 more
doaj +1 more source
Well-differentiated thyroid cancer disclosed during pregnancy. Management experience
Thyroid cancer have the second place as malignancy detectable during pregnancy. Disclose of thyroid cancer during pregnancy raises many questions among endocrinologists, oncologists and obstetricians.
A. A. Ilyin +8 more
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Risk stratification of neck lesions detected sonographically during the follow-up of differentiated thyroid cancer [PDF]
Context: The European Thyroid Association (ETA) has classified post-treatment cervical ultrasound findings in thyroid cancer patients based on their association with disease persistence/recurrence.
BIFFONI, Marco +12 more
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CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]
The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro +15 more
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BackgroundPediatric papillary thyroid cancer presents with a more advanced stage of disease than adult PTC; and it is more likely to be aggresive and distant metastases, although the survival rate is high.MethodsA retrospective observational study was ...
Rui Du +13 more
doaj +1 more source
Mutational Analysis in Pediatric Thyroid Cancer and Correlations with Age, Ethnicity, and Clinical Presentation. [PDF]
BackgroundWell-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most being papillary thyroid carcinoma (PTC). The objective of the study was to assess the prevalence of different mutations in pediatric WDTC and correlate the ...
Cheng, Shih-Min +9 more
core +1 more source
Fibronectin-1 expression is increased in aggressive thyroid cancer and favors the migration and invasion of cancer cells [PDF]
n this study we analyzed the expression levels of markers of epithelial-to-mesenchymal transition (EMT) in several papillary thyroid carcinomas (PTCs) and the relation with tumor genotypes and clinicopathological characteristics.
Bulotta, Stefania +11 more
core +1 more source
Metformin treatment for diabetes mellitus correlates with progression and survival in colorectal carcinoma [PDF]
BACKGROUND: Diabetes mellitus is unfavorably associated with cancer risk. The purpose of this multi-disciplinary project was to evaluate a possible association of diabetes mellitus and other comorbidities and their treatment with progression of ...
Brown, Robert E. +10 more
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EGF and TGF-β1 effects on thyroid function [PDF]
Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF-β receptors, as
Gabriella Mincione +7 more
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Positive Surgical Margins in the 10 Most Common Solid Cancers. [PDF]
A positive surgical margin (PSM) following cancer resection oftentimes necessitates adjuvant treatments and carries significant financial and prognostic implications.
Califano, Joseph A +14 more
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