Results 101 to 110 of about 59,250 (306)

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

open access: yesAdvanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma   +10 more
wiley   +1 more source

The correlation study between the glucose metabolism of 18F-FDG PET/CT incidental thyroid cancer and clinicopathologic characteristics

open access: yesZhongguo aizheng zazhi, 2016
Background and purpose: The proportion of incidental thyroid cancer in PET imaging was significantly increased with the wide application of 18F-FDG PET/CT.
李雪娜, 尹雅芙, 杜补林
doaj  

Pharmacological Therapy of Differentiated Thyroid Cancer

open access: yes, 2018
The Thyroid is a magnificent endocrinal organ that have an effect on the whole body. Thyroid cancer is not as common as other solid tumors are, but in its aggressive and metastatic form is very devastating and difficult to treat.
Frenkel, Yulia
core  

Preoperative Radiological Staging of Well Differentiated Thyroid Cancer [PDF]

open access: yes, 2008
Preoperative staging of thyroid cancer is essential for radiologist to help the surgeon manage the patient. Ultrasonography plays an important first role in diagnostic work-up. CT, MRI and PET also can do complementary role.
곽진영, 김은경
core  

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

open access: yesAdvanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu   +10 more
wiley   +1 more source

Unusual Presentation of Differentiated Thyroid Cancer Metastasis

open access: yesInternational Archives of Otorhinolaryngology, 2018
Introduction The rates of thyroid cancers are on a rise, especially well-differentiated thyroid cancers. This could be partly due to newer diagnostic modalities, like high-resolution ultrasound, that can pick up smaller lesions.
Haissan Iftikhar   +3 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

Is radioiodine administration in patients with papillary thyroid multifocal microcarcinoma unnecessary?

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2016
Radioiodine (RAI) has played a crucial role in differentiated thyroid cancer treatment for more than 60years. However, the use of RAI administration in patients with papillary thyroid microcarcinoma (even multifocal) is now being widely discussed and ...
Eva Krčálová   +8 more
doaj   +1 more source

Anaplastic thyroid carcinoma: novel therapeutic targets and strategies

open access: yes, 2008
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies, with a mean survival of only 6 months. Therefore, novel therapeutic approaches are desperately required. - dl1520 is a replication competent adenovirus that, due to lack
Libertini, Silvana
core  

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan   +11 more
wiley   +1 more source

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