Results 131 to 140 of about 3,508,804 (299)
Animal Models and Experimental Medicine, EarlyView.A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen +11 more
wiley +1 more source
Hepatology, EarlyView., 2022 Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai +29 more
wiley +1 more source
Nanomaterials facilitating optical therapy for thyroid cancer: research progress and prospects
Materials & DesignThyroid cancer is the most common malignant tumor of the endocrine system, and Papillary Thyroid Cancer (PTC) is the most common. For differentiated thyroid cancer (DTC), surgery is the most important treatment modality, which is most widely used in ...
Jiedong Kou +5 more
doaj +1 more source
, 2022 Thyroid cancer is the most common endocrine malignancy with approximately 700 new cases in The Netherlands in 2018. Differentiated thyroid cancer (DTC), comprising both papillary (PTC) and follicular thyroid cancer (FTC), is the most frequent (80-85%) form of thyroid cancer.
openaire +1 more source
Arthritis &Rheumatology, EarlyView.Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang +16 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective To assess the association between duration of targeted therapy exposure and cancer risk in patients with spondyloarthritis (SpA), including those with psoriatic arthritis, axial SpA, and other subtypes. Methods This nationwide cohort study used the French health insurance database to identify adults with SpA initiating a targeted therapy ...
Karine Tankovic +7 more
wiley +1 more source
Cancer in Systemic Sclerosis: Clinical Associations and Prognostic Impact From the EUSTAR Registry
Arthritis &Rheumatology, EarlyView.Objective Cancer represents a major cause of death in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti‐RNA polymerase III (POLR3)–positive disease, needing further exploration. Methods We performed a nested case‐control study within the European Scleroderma Trials and Research group ...
Antonio Tonutti +52 more
wiley +1 more source
Combining Transfer of TTF-1 and Pax-8 Gene: a Potential Strategy to Promote Radioiodine Therapy of Thyroid Carcinoma [PDF]
, 2011 Cotransfer of TTF-1 and Pax-8 gene to tumor cells, resulting in the reexpression of iodide metabolism-associated proteins, such as sodium iodide symporter (NIS), thyroglobulin (Tg), thyroperoxidase (TPO), offers the possibility of radioiodine therapy to ...
Da Mu +4 more
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Autism Research, EarlyView.ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl +6 more
wiley +1 more source
, 2013 Background: Adjuvant radiotherapy is indicated in differentiated thyroid cancer patients with high risk of local recurrence, either macroscopic residual disease or extensive nodal involvement.
Lee, VHF +5 more
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