Results 31 to 40 of about 1,127,844 (304)

Case report: Visibly curative effect of dabrafenib and trametinib on advanced thyroid carcinoma in 2 patients

Frontiers in Oncology, 2023
BackgroundDifferentiated thyroid cancer accounts for the majority of thyroid cancers and has a good prognosis after standard treatment. However, there are still some complex and refractory thyroid cancers, including locally advanced differentiated ...
Xue Peng, Jianyong Lei, Zhihui Li, Kun Zhang   +3 more
doaj   +1 more source

Selective vagus–recurrent laryngeal nerve anastomosis guided by intraoperative neuromonitoring: evidence of lateral motor fiber clustering in the vagus nerve

Frontiers in Endocrinology
ObjectiveDirect anastomosis (DA) is the standard approach after recurrent laryngeal nerve (RLN) transection but is often not feasible due to excessive tension.
Jiedong Kou, Daqi Zhang, Le Zhou, Shijie Li, Tie Wang, Peiyao Wang, Zihan Zhao, Gianlorenzo Dionigi, Carla Colombo, Yishen Zhao, Hui Sun   +10 more
doaj   +1 more source

Functional role of the CXCR4 chemokine receptor in thyroid cancer [PDF]

, 2009
Thyroid cancer is the most common endocrine malignancy and its incidence is increasing worldwide. We previously found that normal rat thyroid cells, transduced with papillary thyroid cancer (PTC)-related oncogenes, display an inflammatory signature, that
Avilla, Elvira
core   +1 more source

Evaluation of the first automated thyroglobulin assay [PDF]

, 1999
The aim of this study was to investigate technical and analytical performance of the first automated thyroglobulin (Tg) assay (DPC-Immulite(R); Diagnostic Products Corporation, Los Angeles, USA).
Jacob, Karl, Seidel, Dietrich, Vogeser, Michael, Knesewitsch, Peter   +3 more
core   +1 more source

Histopathological Assessment for Papillary Thyroid Carcinoma

, 2022
Histologic assessments of papillary thyroid carcinoma are crucial for management of patients with the cancer as well as research on the cancer as papillary thyroid carcinoma has different histologic subtypes and many parameters which are essential in ...
Lam, AK
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

The role of age and antibodies in central regional lymph node metastases of papillary thyroid carcinoma combined with hashimoto’s thyroiditis

BMC Cancer
Background The coexistence of Hashimoto thyroiditis (HT) and papillary thyroid carcinoma (PTC) is increasing year by year, and the role of age, thyroglobulin antibodies (TgAb), and thyroid peroxidase antibodies (TPOAb) in central neck lymph node ...
Chengcheng Duan, Ping Yu, Xinran Wei, Jingyue Zhong, Xianji Wu, Siqi Xiao, Guang Zhang   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Interobserver agreement of Thyroid Imaging Reporting and Data System (TIRADS) and strain elastography for the assessment of thyroid nodules [PDF]

, 2013
Background: Thyroid Imaging Reporting and Data System (TIRADS) was developed to improve patient management and cost-effectiveness by avoiding unnecessary fine needle aspiration biopsy (FNAB) in patients with thyroid nodules.
Stefan Zeuzem, Herrmann, Eva, Friedrich-Rust, Mireen, Dauth, Nina, Bogdanou, Dimitra, Christian Berner, Nina Dauth, Mireen Friedrich-Rust, Bojunga, Jörg, Dimitra Bogdanou, Joerg Bojunga, Gesine Meyer, Eva Herrmann, Berner, Christian, Meyer, Gesine, Zeuzem, Stefan   +15 more
core   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source