Results 51 to 60 of about 1,127,844 (304)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Endocrinology Research and Practice, 2022 Objective: Coexistence of primary hyperparathyroidism and differentiated thyroid carcinoma has been reported from time to time. However, the clinical features and risk factors of this association are unclear.
Emine Kartal Baykan +5 more
doaj
Di-san junyi daxue xuebao, 2019 Objective To identify the differentially expressed proteins between differentiated thyroid carcinoma and radioiodine-refractory differentiated thyroid carcinoma, explore the pathogenetic mechanism of radioiodine-refractory differentiated thyroid ...
LI Yunjie +3 more
doaj +1 more source
Loss of primary cilia promotes mitochondria-dependent apoptosis in thyroid cancer
Scientific Reports, 2021 The primary cilium is well-preserved in human differentiated thyroid cancers such as papillary and follicular carcinoma. Specific thyroid cancers such as Hürthle cell carcinoma, oncocytic variant of papillary thyroid carcinoma (PTC), and PTC with ...
Junguee Lee +6 more
doaj +1 more source
[Poorly differentiated thyroid carcinoma : An underdiagnosed entity. German version]. [PDF]
, 2019 Poorly differentiated thyroid carcinomas (PDTCs) are a rare subtype of thyroid carcinomas that are biologically situated between well-differentiated papillary/follicular thyroid carcinomas and anaplastic thyroid carcinomas (ATCs).The diagnosis of ...
Komminoth, P +3 more
core +1 more source
Concepts of Pathological Staging and Prognosis in Papillary Thyroid Carcinoma
, 2022 American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (AJCC/UICC) staging and American Thyroid Association (ATA) risk predication system are the best predicators of mortality and cancer recurrence, respectively, in patients ...
Lam, AK
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Patient and Surgeon Candidacy for Transoral Endoscopic Thyroid Surgery
Turkish Archives of Otorhinolaryngology, 2019 The transoral thyroidectomy (TT) is a feasible novel surgical procedure that does not need visible incisions, a truly cutaneous scar-free surgery. Inclusion criteria are (a) patients who have a ultrasonographically (US) estimated thyroid diameter not ...
Fausto Fama +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Cancer Cell InternationalBackground Pyroptosis, an inflammatory form of programmed cell death, has been implicated in the pathogenesis and progression of several cancers. However, the significance of pyroptosis-related genes (PRGs) in papillary thyroid cancer (PTC) remains ...
Fang Li +10 more
doaj +1 more source