Results 241 to 250 of about 4,638,915 (335)

Research Progress on the Regulatory Effect of Curcumin on Mesenchymal Stem Cells. [PDF]

Int J Mol Sci
Sun L, Hu D, Dong X, Wang R, He W, Pan Y, Li P, Xing X.   +7 more
europepmc   +1 more source

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

, 2013
Julia Esser‐von Bieren, Ilaria Mosconi, Romain Guiet, Alessandra Piersgilli, Beatrice Volpe, Fei Chen, William C. Gause, Arne Seitz, J. Sjef Verbeek, Nicola Harris   +9 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells

, 2015
Bernard Khor, John D Gagnon, Gautam Goel, Marly I. Roche, Kara L. Conway, Khoa Tran, Leslie N. Aldrich, Thomas B. Sundberg, Alison M. Paterson, Scott Mordecai, David Dombkowski, Melanie Schirmer, Pauline H. Tan, Atul K. Bhan, Rahul Roychoudhuri, Nicholas P. Restifo, John J. O’Shea, Benjamin D. Medoff, Alykhan F. Shamji, Stuart L. Schreiber, Arlene H. Sharpe, Stanley Y. Shaw, Ramnik J. Xavier   +22 more
openalex   +2 more sources

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

RETRACTION: CXCL13 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Inhibiting miR-23a Expression. [PDF]

Stem Cells Int
International SC.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

METTL14-mediated RNA m⁶A modifications of TET1 and TET2 in duck myoblast differentiation. [PDF]

Poult Sci
Liu J, Wu J, Liao Z, Wang Y, Xiao X, Chai X, Wei W, Liao W, Tang C, Hu X, Xu J, Mao H, Liu S, Chen B.   +13 more
europepmc   +1 more source

Role of inflammatory markers in differentiation and prognostication of gliomas – A prospective cohort study

Praveen Ravichandran, Manoranjithakumari Mani, Ramesh Andi Sadayandi   +2 more
openalex   +2 more sources