Results 71 to 80 of about 293,677 (256)

Prediction of COVID-19 spread with models in different patterns: A case study of Russia

open access: yesOpen Physics
This study deals with a mathematical model that examines the spread of Coronavirus disease (COVID-19). This model has been handled with different processes such as deterministic, stochastic, and deterministic–stochastic. First of all, a detailed analysis
Cetin Mehmet Akif, Araz Seda Igret
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Differentiation of European Integration Process [PDF]

open access: yes, 2012
Hlavním cílem práce s názvem Diferenciace evropského integračního procesu je historický exkurz do problematiky diferenciace a flexibility ve vývoji vztahů mezi jednotlivými členskými zeměmi evropské integrace.
Svobodová, Tereza
core  

Some formulae for numerical differentiation and integration of analytic functions

open access: yesJournal of Numerical Analysis and Approximation Theory, 1981
Not available.
Dorel Homentcovschi
doaj   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Quality Product differentiation in Cee-Eu Intra-Industry Trade [PDF]

open access: yes
In this paper we compute price/quality gap indicators to measure vertical intra-iundustry trade (VIIT) in EU markets at 3-digit NACE industry level. These indicators are then used to test some hypotheses relative to the determinants of the quality of ...
Anna Maria Ferragina
core  

The European Union as a System of Differentiated Integration: Interdependence, Politicization and Differentiation. IHS Political Science Series No. 137, 10 July 2014 [PDF]

open access: yes, 2014
This paper conceptualizes the European Union (EU) as a system of differentiated integration characterized by both variation in levels of centralization (vertical differentiation) and variation in territorial extension (horizontal differentiation ...
Leuffen, Dirk   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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