Results 181 to 190 of about 196,920 (284)

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

open access: yesAdvanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang   +7 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Differentiation of Human Induced Pluripotent Stem Cells Toward Implantable Chondroprogenitor Cells. [PDF]

open access: yesCartilage
Ekholm J   +9 more
europepmc   +1 more source

Molecular‐Level Insights into Interfacial Adsorption Mechanisms of PFOA on Functional Dolomite Surfaces via AIMD and Spectroscopy

open access: yesAdvanced Materials Interfaces, EarlyView.
Perfluorooctanoic acid (PFOA), ab initio molecular dynamics (AIMD), density functional theory (DFT), Dolomite (DL), metal‐organic frameworks (MOFs), calcined modified dolomite (CDL), zero‐point of charge (PZC), metal‐organic frameworks (MOFs), Fourier transform infrared (FTIR), X‐ray diffraction (XRD), scanning electron microscopy (SEM ...
Yating Yang   +8 more
wiley   +1 more source

Impact of Oxygen Plasma Pre‐Treatment on Thermal Oxidation and Reliability of SiO2 on 4H‐SiC

open access: yesAdvanced Materials Interfaces, EarlyView.
We investigate how oxygen plasma pre‐treatment affects the thermal oxidation of silicon carbide. While plasma modification increases growth rates by 84%, it reduces dielectric breakdown strength by 18%. Our findings reveal that although plasma improves the interface state density, it introduces structural damage, highlighting a critical trade‐off ...
Chezhiyan Nanjappan   +3 more
wiley   +1 more source

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