Results 91 to 100 of about 1,898,530 (318)

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Reasons of sleeping difficulties as perceived by adolescents [Elektronisk resurs]

, 2020
BackgroundSleeping difficulties are growing among adolescents worldwide. Research shows relationships between sleeping difficulties and reduced learning ability, memory impairment, hyperactivity, poorer school performance, lower grades, and increased ...
Jakobsson, Malin,, Josefsson, Karin,, Högberg, Karin   +2 more
core  

STUDENTS' DIFFICULTIES IN ENGLISH LISTENING COMPREHENSION: A DESCRIPTIVE RESEARCH AT THAI NGUYEN UNIVERSITY OF INFORMATION AND COMMUNICATION TECHNOLOGY, THAI NGUYEN UNIVERSITY

Tạp chí Khoa học
This study attempts to ascertain the common listening comprehension challenges that students at the University of Information and Communications Technology, Thai Nguyen University (ICTU) often encounter in listening and understanding English.
Dang Phuong Mai, Pham Thuy Hang
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

To get hold of the wrong end of the stick : reasons for poor idiom understanding in children with reading comprehension difficulties. [PDF]

, 2008
Purpose: The aim was to identify the source of idiom understanding difficulties in children with specific reading comprehension failure. Method: Two groups (Ns=15) of 9- to 10-year-olds participated. One group had age-appropriate word reading and reading
Cain, Kate, Towse, Andrea S.
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Supported employment : persons with learning difficulties in Malaysia [PDF]

Many studies in the minority world have emphasized the potentially positive influences of supported as opposed to sheltered employment on the inclusion of persons with disabilities, including learning difficulties, into the mainstream economy and ...
Wan Abdullah, Wan Arnidawati
core  

Reasons of sleeping difficulties as perceived by adolescents

, 2020
Background Sleeping difficulties are growing among adolescents worldwide. Research shows relationships between sleeping difficulties and reduced learning ability, memory impairment, hyperactivity, poorer school performance, lower grades, and increased ...
Jakobsson, Malin, Josefsson, Karin, Högberg, Karin   +2 more
core  

Unveiling critical reading strategies and challenges: a mixed-methods study among English major students in a Vietnamese higher education institution

Cogent Education
The objective of this study is to evaluate the critical reading (CR) strategies utilized by English major students at a university in Vietnam, identifying both frequently employed and underutilized tactics.
Ha Van Le, Thi Ai Duyen Nguyen, Dinh Hieu Ngan Le, Phuong Uyen Nguyen, Thi Thien An Nguyen   +4 more
doaj   +1 more source