Results 121 to 130 of about 420,207 (298)

Item analysis of multiple choice questions from assessment of health sciences students, Tigray, Ethiopia

open access: yesBMC Medical Education
Background Rapid expansion of higher education and graduation rate in Ethiopia, doesn’t tell much about quality of core processes like teaching and learning. Despite the fact that preparation of a good item is essential, little attention has been paid to
Mengistu Welday Gebremichael   +3 more
doaj   +1 more source

“Comparative impact of body mass index, waist circumference, and a body shape index on surgical difficulty in laparoscopic cholecystectomy: A cross-sectional comparative study”

open access: yes
Background:Laparoscopic cholecystectomy (LC) is the preferred minimally invasive treatment for symptomatic gallstones, but surgical difficulty can vary, sometimes causing complications or conversion to open surgery.
Swaroop Sanat Sahu   +5 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

The Entropy of a Rapid Aimed Movement: Fitts’ Index of Difficulty versus Shannon’s Entropy

open access: yes, 2011
Part 1: Long and Short PapersInternational audienceA thought experiment is proposed that reveals a difference between Fitts’ index of difficulty and Shannon’s entropy, in the quantification of the information content of a series of rapid aimed movements.
Ren, Xiangshi   +6 more
core   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall   +9 more
wiley   +1 more source

Analysis of Difficulty Index, Discrimination Index and Distractor Efficiency in Multiple Choice Questions

open access: yes
Background: The item analysis of multiple-choice questions (MCQs) is an essential tool that can provide input on validity and reliability of items. It helps to identify items, which can be revised or discarded, thus building a quality MCQ bank.
Moadeyah Mohammed Alasmari   +7 more
core   +1 more source

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