Results 51 to 60 of about 1,485,281 (291)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Spherical Harmonic Family of Beampatterns

Acoustics, 2022
The free space solution to the wave equation in spherical coordinates is well known as a separable product of functions. Re-examination of these functions, particularly the sums of spherical Bessel and harmonic functions, reveals behaviors which can ...
Kevin J. Parker, Miguel A. Alonso
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diffraction in grating optical filters with angular-selective light transmission [PDF]

Компьютерная оптика, 2020
The effect of diffraction on the directional light transmittance of grating optical filters designed for smart windows is studied. The filter has an angular selective light transmission due to two thin-film gratings formed by "non-transmissive ...
R.S. Zakirullin
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Uncovering the Mechanisms of Long-Range Magnetic Order in [Mn(mal)(H₂O)]_n: Insights from Microscopic and Macroscopic Magnetic Analysis

Magnetochemistry
In this study, we investigate the magnetic properties of the molecular compound [Mn(mal)(H2O)]ₙ (mal = dianion of malonic acid) by integrating microscopic and macroscopic characterization, combining unpolarized neutron diffraction and magnetometry ...
Fernando S. Delgado, Laura Cañadillas-Delgado, Juan Rodríguez-Carvajal, Óscar Fabelo, Jorge Pasán   +4 more
doaj   +1 more source

NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius

Scientific Reports, 2018
Ketol-acid reductoisomerase (KARI) is a bifunctional enzyme in the second step of branched-chain amino acids biosynthetic pathway. Most KARIs prefer NADPH as a cofactor.
Chin-Yu Chen, Tzu-Ping Ko, Kuan-Fu Lin, Bo-Lin Lin, Chun-Hsiang Huang, Cheng-Hung Chiang, Jia-Cherng Horng   +6 more
doaj   +1 more source

Surface Plasmons Excited by X-rays in the Surface Layers of Solids

Solids, 2022
The phenomenon of total external reflection of X-rays at a sliding angle of incidence of a beam of incident X-rays is investigated. For metals, a quantitative law of direct dependence of the refractive index decrement on the interplane distance is ...
Valery M. Stozharov
doaj   +1 more source

Correlations in interference and diffraction

, 1997
Quantum formalism of Fraunhofer diffraction is obtained. The state of the diffraction optical field is connected with the state of the incident optical field by a diffraction factor.
Born M., Duan L. M., Fisz M., Gardiner C. W., Guang-Can Guo, Klauder J. R., Lu-Ming Duan, Racah G.   +7 more
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source