A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration [PDF]
Axonal degeneration is a molecular self-destruction cascade initiated following traumatic, toxic, and metabolic insults. Its mechanism underlies a number of disorders including hereditary and diabetic neuropathies and the neurotoxic side effects of ...
Bhattacharya, Martha R.C.+7 more
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Single Low-Dose Lipopolysaccharide Preconditioning: Neuroprotective Against Axonal Injury and Modulates Glial Cells [PDF]
AIM: Over 7 million traumatic brain injuries (TBI) are reported each year in the United States. However, treatments and neuroprotection following TBI are limited because secondary injury cascades are poorly understood.
Huber, Jason D.+7 more
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Outcome of severe traumatic brain injury at a critical care unit: a review of 87 patients [PDF]
OBJECTIVE: To determine the outcome of severe traumatic brain injury and to document the factors influencing mortality. DESIGN: A six months prospective study.
Mwangombe, NJM, Opondo, EA
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Background: Erythropoietin (EPO) as a major stimulator of red blood cell (RBC) production play a key role on brain protection and have a caring effect on neurons from hypoxic or traumatic injury.
Saeid Abrishamkar+2 more
doaj
Endogenous transforming growth factor β1 suppresses inflammation and promotes survival in adult CNS [PDF]
Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system.
Bauer, K+12 more
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In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study [PDF]
Traumatic brain injury causes diffuse axonal injury and loss of cortical neurons. These features are well recognized histologically, but their in vivo monitoring remains challenging. In vivo cortical microdialysis samples the extracellular fluid adjacent
Adekoya+86 more
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Introduction: Traumatic axonal injury (TAI), a head injury condition formerly known as diffuse axonal injury, results from direct mechanical forces causing multiple scattered lesions, either haemorrhagic or non-haemorrhagic, within brain tissue.
Ahmad Faried+4 more
doaj +1 more source
Value of MRI in paediatric closed head injury
Children (and less commonly adults) with a low level of conciousness following acute head injury who have a normal CT sean are often assumed to have diffuse axonal injury of the brain.
Savvas Andronikou+2 more
doaj +1 more source
Semiquantitative analysis of corpus callosum injury using magnetic resonance imaging indicates clinical severity in patients with diffuse axonal injury [PDF]
Makoto Takaoka
openalex +1 more source
A High Rate Tension Device for Characterizing Brain Tissue
The mechanical characterization of brain tissue at high loading velocities is vital for understanding and modeling Traumatic Brain Injury (TBI). The most severe form of TBI is diffuse axonal injury (DAI) which involves damage to individual nerve cells ...
Destrade, Michel+2 more
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