Results 151 to 160 of about 22,064 (234)

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag   +14 more
wiley   +1 more source

Early Detection of Neuroinflammation and White Matter Damage Following Dorsal Spinal Nerve Root Sectioning in a Nonhuman Primate Model

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Dorsal rhizotomy, or spinal dorsal nerve root lesioning, is a surgical procedure used to treat intractable nerve pain by selectively severing sensory afferent nerve roots. This study aimed to evaluate whether multiparametric MRI, including diffusion tensor imaging (DTI), quantitative magnetization transfer (qMT), chemical exchange ...
Feng Wang, John C. Gore, Li Min Chen
wiley   +1 more source

Informed Dictionary‐Guided Monte Carlo Inversion for Robust and Reproducible Multidimensional MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a robust and efficient multidimensional MRI (MD‐MRI) data processing framework for accurately estimating joint frequency‐dependent diffusion‐relaxation distributions, while overcoming computational limitations and noise instability inherent to Monte Carlo (MC) inversion.
Joon Sik Park   +3 more
wiley   +1 more source

The Concept and Pathological Mechanism of Diffuse Axonal Injury

open access: bronze, 2022
Raikint Jain   +6 more
openalex   +1 more source

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

open access: yesRare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu   +8 more
wiley   +1 more source

Multi‐Channel Neural Interface for Neural Recording and Neuromodulation

open access: yesSmall Methods, EarlyView.
This review highlights recent advances in multi‐channel neural interface technologies, covering both high‐resolution electrophysiological recording systems and multifunctional platforms with integrated capabilities. It also discusses innovations in structure and materials for reduced invasiveness, state‐of‐the‐art data analysis, including machine ...
Eunmin Kim   +9 more
wiley   +1 more source

Blood Pressure Variability and Outcome Predictors for Traumatic Brain Injury Patients with Diffuse Axonal Injury: A Retrospective Cohort Study. [PDF]

open access: yesWest J Emerg Med
Ren CE   +9 more
europepmc   +1 more source

Diffuse Axonal Injury Grade on Early MRI is Associated with Worse Outcome in Children with Moderate-Severe Traumatic Brain Injury. [PDF]

open access: yesNeurocrit Care, 2022
Janas AM   +7 more
europepmc   +1 more source

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