Large deviations for sticky-reflecting Brownian motion with boundary diffusion [PDF]
We study a Schilder-type large deviation principle for sticky-reflected Brownian motion with boundary diffusion, both at the static and sample path level in the short-time limit. A sharp transition for the rate function occurs, depending on whether the tangential boundary diffusion is faster or slower than in the interior of the domain.
arxiv
A historical look using virtual microscopy: the first case report of adrenomyeloneuropathy (AMN). [PDF]
Budka H.
europepmc +1 more source
Endocrine dysfunction in adrenoleukodystrophy. [PDF]
Engelen M, Kemp S, Eichler F.
europepmc +1 more source
Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis [PDF]
Diffusion kurtosis imaging (DKI), is an imaging modality that yields novel disease biomarkers and in combination with nervous tissue modeling, provides access to microstructural parameters. Recently, DKI and subsequent estimation of microstructural model parameters has been used for assessment of tissue changes in neurodegenerative diseases and their ...
arxiv
A reaction-diffusion model for relapsing-remitting multiple sclerosis with a treatment term [PDF]
We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines, consumption of myelin sheath due to anomalously activated lymphocytes and its restoration by oligodendrocytes ...
arxiv
Clinical and Radiologic Features, Pathology, and Treatment of Baló Concentric Sclerosis. [PDF]
Jolliffe EA+6 more
europepmc +1 more source
Derivation from kinetic theory and 2-D pattern analysis of chemotaxis models for Multiple Sclerosis [PDF]
In this paper, a class of reaction-diffusion equations for Multiple Sclerosis is presented. These models are derived by means of a diffusive limit starting from a proper kinetic description, taking account of the underlying microscopic interactions among cells.
arxiv
Empowering Dysarthric Speech: Leveraging Advanced LLMs for Accurate Speech Correction and Multimodal Emotion Analysis [PDF]
Dysarthria is a motor speech disorder caused by neurological damage that affects the muscles used for speech production, leading to slurred, slow, or difficult-to-understand speech. It affects millions of individuals worldwide, including those with conditions such as stroke, traumatic brain injury, cerebral palsy, Parkinsons disease, and multiple ...
arxiv
Voxel-wise Weighted MR Image Enhancement using an Extended Neighborhood Filter [PDF]
We present an edge preserving and denoising filter for enhancing the features in images, which contain an ROI having a narrow spatial extent. Typical examples include angiograms, or ROI spatially distributed in multiple locations and contained within an outlying region, such as in multiple-sclerosis.
arxiv
Normative Diffusion Autoencoders: Application to Amyotrophic Lateral Sclerosis [PDF]
Predicting survival in Amyotrophic Lateral Sclerosis (ALS) is a challenging task. Magnetic resonance imaging (MRI) data provide in vivo insight into brain health, but the low prevalence of the condition and resultant data scarcity limit training set sizes for prediction models.
arxiv