Results 171 to 180 of about 180,429 (290)

Decreased renal function predicts severe cytokine release syndrome after CAR‐T‐cell therapy for large B‐cell lymphoma

British Journal of Haematology, EarlyView.
Summary Cytokine release syndrome (CRS) remains a major toxicity of chimeric antigen receptor (CAR) T‐cell therapy in large B‐cell lymphoma (LBCL), and robust pre‐infusion predictors are needed for risk‐adapted management. We retrospectively analysed LBCL patients in the Japanese nationwide registry who underwent CD19 CAR‐T‐cell therapy between 2019 ...
Yasuyuki Arai, Tomoyasu Jo, Takayuki Sato, Masatoshi Sakurai, Daisuke Kaji, Toshio Kitawaki, Kazuyuki Shimada, Tatsu Shimoyama, Satoshi Yoshihara, Shinichi Makita, Nobuharu Fujii, Go Yamamoto, Keisuke Kataoka, Emiko Sakaida, Hideki Goto, Yasuhiro Nakashima, Akiyo Yoshida, Yoshihiro Umezawa, Haryoon Kim, Motohiro Kato, Yoshiko Atsuta, Koji Kato   +21 more
wiley   +1 more source

Subcutaneous abdominal wall involvement in diffuse large B-cell lymphoma: case report. [PDF]

Front Oncol
Xu D, Guo B, Li M, Zhang Y.
europepmc   +1 more source

Curcumin induces and enhances the PARP1-mediated parthanatos in diffuse large B cell lymphoma. [PDF]

Oncol Lett
Wang Y, Qi R, Zhao X, Mei H, Qiu M, Liu F, Wang H.   +6 more
europepmc   +1 more source

Contrast‐enhanced ultrasonography vs MRI for indeterminate testicular lesions: a systematic review and meta‐analysis

BJU International, EarlyView.
Objective To conduct a systematic review and meta‐analysis to indirectly compare the diagnostic performance of contrast‐enhanced ultrasonography (CEUS) and magnetic resonance imaging (MRI) in the evaluation of indeterminate testicular lesions and to explore their potential roles in guiding clinical decision‐making.
Muhammed Arif Ibis, Maria Satchi, Nicholas Raison, Hakan Bahadır Haberal, Araz Musaev, Tet Yap, Angelo Territo, Cagri Akpinar, Giuseppe Fallara, Dean Y. Huang, Murat Gul, Asif Muneer, Antonio Ruffo, Omer Onur Cakir, Fabio Castiglione   +14 more
wiley   +1 more source

Prognostic impact of TP53 mutations in diffuse large B-cell lymphoma. [PDF]

Ann Hematol
Yu J, He Q, Yan Y, Liu K, Xie R, Ma J, Wang L.   +6 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Novel immunotherapeutic strategies for diffuse large B-cell lymphoma: a comprehensive review. [PDF]

Front Immunol
Li Y, Zhang Y, Zhu C, Han Y, Gao X, Yue J, Wang Y.   +6 more
europepmc   +1 more source

MAP17 Enhances Chemoresistance and Tumorigenicity of Glioblastoma‐Initiating Cells via the Canonical NF‐кB Pathway

Cancer Science, EarlyView.
MAP 17 is identified as highly expressed in TMZ‐resistant glioblastoma‐initiating cells (GICs). MAP17 enhances GIC proliferation, TMZ resistance, and tumorigenicity through NF‐κB/RELA‐dependent BCL2 upregulation. ABSTRACT Glioblastoma (GBM) is the most common malignant brain tumor in adults.
Shenshen Dou, You Lee Son, Toru Kondo
wiley   +1 more source

The impact of clinical manifestations on the prognosis of diffuse large B-cell lymphoma. [PDF]

Ther Adv Hematol
Wang S, Xu X, Ma Y, Qian S, Tang L, Sun L, Shen Z, Ye H, Qian H, Jiang S, Zhou S.   +10 more
europepmc   +1 more source

Bispecific Ligand‐Based EphB4 CAR‐T Cells Generated Using Ephrin‐B2 Show Potent Antitumor Activity Against Lung Adenocarcinoma

Cancer Science, EarlyView.
EphB4 and EphA2 positivity in lung adenocarcinoma samples was high. Ligand‐based EphB4 CAR‐T cells exhibit bispecificity, targeting both EphB4 and EphA2. EphB4 CAR‐T cells exert significant antitumor effects against lung adenocarcinoma. ABSTRACT Chimeric antigen receptor (CAR)‐T cells generated using ephrin‐B2, the natural ligand for ephrin type‐B ...
Hirotaka Kumeda, Koichi Hirabayashi, Shuji Mishima, Kotaro Morita, Yu Furui, Marina Fujioka, Tomoyuki Nakajima, Miyuki Tanaka, Yoshinori Sato, Takeshi Uehara, Shigeki Yagyu, Kimihiro Shimizu, Yozo Nakazawa   +12 more
wiley   +1 more source