Results 101 to 110 of about 25,184 (248)

New progress in the treatment of diffuse midline glioma with H3K27M alteration

Heliyon
Diffuse midline glioma with H3K27 M alteration is a primary malignant tumor located along the linear structure of the brain, predominantly manifesting in children and adolescents.
Zhi Yang, Liang Sun, Haibin Chen, Caixing Sun, Liang Xia   +4 more
doaj   +1 more source

Neurological update: gliomas and other primary brain tumours in adults. [PDF]

, 2017
The emerging understanding of molecular changes in a wide range of brain tumours has led to a significant shift in how these tumours are diagnosed, managed and treated.
Brandner, S, Jaunmuktane, Z
core   +1 more source

Development of a Novel Extracellular Vesicle‐Based Biomarker Approach for Pediatric High‐Grade Glioma

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Pediatric high‐grade gliomas (pHGGs) account for 20% of childhood brain tumours and are associated with poor survival. Currently, pHGG detection relies on MRI, a costly and time‐consuming procedure. Extracellular vesicles (EVs) carry molecular markers indicative of their cellular origin and can be isolated from various biofluids, offering an ...
Adriana Fernandez Garcia, Poorvi Iyer, Pablo Ashi, Ibukunoluwa Tella, Vennela Sangaraboina, Dhruv Bhagat, Chelva Janarthanam, Alejandra Bargues‐Carot, Anumantha G. Kanthasamy, Thomas Spoerer, Morgane E. Golan, Steven L. Stice, Kosuke Funato   +12 more
wiley   +1 more source

Comprehensive profiling of stem-like features in pediatric glioma cell cultures and their relation to the subventricular zone

Acta Neuropathologica Communications, 2023
Pediatric high-grade gliomas (pHGG) are brain tumors occurring in children and adolescents associated with a dismal prognosis despite existing treatments. Therapeutic failure in both adult and pHGG has been partially imputed to glioma stem cells (GSC), a
Marc-Antoine Da-Veiga, Natacha Coppieters, Arnaud Lombard, Bernard Rogister, Virginie Neirinckx, Caroline Piette   +5 more
doaj   +1 more source

T1ρ$$ {}_{1\rho } $$ as a Biomarker for IDH1 Mutation Status in a Glioma Mouse Model

NMR in Biomedicine, Volume 39, Issue 2, February 2026.
Mice bearing IDH1‐mutant and ‐wild‐type glioma underwent quantitative T1ρ$$ {T}_{1\rho } $$ imaging over the course of tumour development. It was found that while IDH1‐wild‐type tumours present similar T1ρ$$ {T}_{1\rho } $$ values as the brain, IDH1‐mutant tumours exhibit significantly higher T1ρ$$ {T}_{1\rho } $$ values compared with the brain. T1ρ$$ {
Hannah J. S. Ehler, Saki Sultana, Christa Davis, Kimberly Brewer, James Rioux   +4 more
wiley   +1 more source

Prognostic factors analysis of diffuse midline glioma

Journal of Neuro-Oncology
Abstract Purpose This study retrospectively analyzes cases of diffuse midline glioma treated with radiotherapy, with the aim of investigating the prognosis of the tumor and its influencing factors. Methods From January 2018 to November 2022, we treated 64 patients who were ...
Jiang, Jing, Li, Wen-bin, Xiao, Shao-wen
openaire   +2 more sources

Neuroendocrine morbidity after pediatric optic gliomas: a longitudinal analysis of 166 children over 30 years [PDF]

, 2015
Context: 50% of pediatric low-grade gliomas affect the optic pathway, hypothalamus and suprasellar areas (OP/HSGs) resulting in significant long-term neuroendocrinopathy.
Aquilina, K, Gan, H-W, Gaze, MN, Hayward, R, Phipps, K, Spoudeas, HA   +5 more
core   +1 more source

RE: Comments on cIMPACT‐NOW Update 11

Brain Pathology, EarlyView.
Henning Leske, Richard Doughty, Pitt Niehusmann   +2 more
wiley   +1 more source

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

Cancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao, Takako Yoshioka, Miho Kato, Kazuyuki Komatsu, Shinichi Tsujimoto, Kenichi Sakamoto, Kazuki Tanimura, Minako Sugiyama, Masahiro Sekiguchi, Yoshiko Nakano, Yoshihiro Otani, Yasushi Yatabe, Akihiko Yoshida, Hajime Okita, Junko Hirato, Kenichi Kohashi, Yukichi Tanaka, Shinji Kohsaka, Takashi Kubo, Kuniko Sunami, Makoto Hirata, Shuichi Tsutsumi, Hiroyuki Aburatani, Katsuyoshi Koh, Masahiro Hirayama, Shuhei Karakawa, Yukayo Terashita, Hiroyuki Fujisaki, Takeshi Yagi, Akihiro Yoneda, Shinji Mochizuki, Hiroyuki Shichino, Tatsuya Suzuki, Tetsuya Takimoto, Koichi Ichimura, Chitose Ogawa, Kimikazu Matsumoto, Hitoshi Ichikawa, Motohiro Kato   +38 more
wiley   +1 more source

Full Issue: Volume 13, Issue 1 - Winter 2018 [PDF]

, 2018
Full Issue: Volume 13, Issue 1 - Winter ...

core   +1 more source