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Developing a zebrafish xenograft model of diffuse midline glioma

open access: yesbioRxiv
Diffuse midline glioma (DMG) is a highly aggressive brain tumor that predominantly affects children. Conventional treatments such as radiation therapy can control progression for a time, but DMG kills nearly 100 percent of patients.
Kaixuan Wang   +10 more
semanticscholar   +3 more sources
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Vanishing Contrast Enhancement of a Diffuse Midline Glioma

Neuropathology
Diffuse midline glioma, is a highly aggressive deep‐seated glioma whose diagnosis must be confirmed through histopathological analysis of stereotactic biopsies.
C. Champeaux Depond   +3 more
semanticscholar   +3 more sources

Dordaviprone (Modeyso) for diffuse midline glioma.

The Medical Letter on Drugs and Therapeutics
Dordaviprone (Modeyso – Jazz), an oral protease activator, has received accelerated approval from the FDA for treatment of diffuse midline gliomas harboring a H3 K27M mutation in patients ≥1 year old who had disease progression following prior treatment.

semanticscholar   +2 more sources

Advances in Treatment of Diffuse Midline Gliomas

Current Neurology and Neuroscience Reports, 2023
Diffuse midline gliomas (DMGs) generally carry a poor prognosis, occur during childhood, and involve midline structures of the central nervous system, including the thalamus, pons, and spinal cord.To date, irradiation has been shown to be the only beneficial treatment for DMG.
Chantel, Cacciotti, Karen D, Wright
openaire   +2 more sources

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