Results 51 to 60 of about 141,795 (265)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
GIScience & Remote Sensing, 2020 Atmospheric aerosols can alter the direct and diffuse components of global solar radiation, which further influences terrestrial gross primary productivity (GPP) via photosynthesis.
Yao Feng, Dongmei Chen, Xinyi Zhao
doaj +1 more source
Environmental Research Letters, 2023 Climate exerts both short-term and long-term impacts on the ecosystem carbon assimilation. However, the main climatic drivers for the variability of gross primary productivity (GPP) remain unclear across various timescales and vegetation types.
Hao Zhou +6 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Astronomy & AstrophysicsWe present the results of a measurement of the near-infrared extragalactic background light (EBL). The surface brightness towards the opaque intermediate-latitude globule DC303.8-14.2 was obtained using ESO VLT/FORS spectrophotometry.
Haikala L. K., Mattila K., Väisänen P.
doaj +1 more source
Diffusive radiation in one-dimensional Langmuir turbulence
Physical Review E, 2007 We calculate spectra of radiation produced by a relativistic particle in the presence of one-dimensional Langmuir turbulence which might be generated by a streaming instability in the plasma, in particular, in the shock front or at the shock-shock interactions.
Fleishman, Gregory D., Toptygin, Igor N.
openaire +3 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source