Results 31 to 40 of about 19,946 (260)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Optical Properties of Living Corals Determined With Diffuse Reflectance Spectroscopy

open access: yesFrontiers in Marine Science, 2019
The internal light field and thus light exposure of the photosymbiotic microalgae (Symbiodinium sp.) in corals is strongly modulated by the optical properties of coral tissue and skeleton.
Steven L. Jacques   +5 more
doaj   +1 more source

Diffuse Reflectance Spectroscopy with Infrared Thermography for Accurate Prediction of Cellulitis

open access: yesJID Innovations, 2021
Cellulitis is frequently misdiagnosed owing to its clinical mimickers, collectively known as pseudocellulitis. This study investigated diffuse reflectance spectroscopy (DRS) alone and in combination with infrared thermography (IRT) for the ...
Adam B. Raff   +10 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Determination of atenolol in pharmaceutical formulations by diffuse reflectance spectroscopy

open access: yesEclética Química, 2018
A simple analytical method for quantification of atenolol in pharmaceutical formulations by diffuse reflectance spectroscopy is described. The method is based on the reaction, on the filter paper surface, between the drug and p-chloranil producing a ...
Mara A. Gotardo   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Determination of hydrochlorothiazide in pharmaceutical formulations by diffuse reflectance spectroscopy

open access: yesEclética Química, 2018
This paper describes a method for quantitative spot test analysis of hydrochlorothiazide using diffuse reflectance spectroscopy. The reflectance measurements were performed analyzing the colored compound (l = 585 nm) produced from the reaction between ...
M. A. Gotardo   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Materiais híbridos orgânico-inorgânicos (ormosil) obtidos por sol-gel com potencial uso como filtro solar

open access: yesQuímica Nova, 2011
This work aimed at the synthesis and characterization of particles of modified silica containing the organic filter dibenzoylmethane (DBM) by the hydrolytic sol-gel method, with modifications to the Stöber route.
Jane K. de F. B. Machado   +5 more
doaj   +1 more source

Structural, diffuse reflectance spectroscopy and dielectric relaxation properties of zirconium (IV) dioxide

open access: yesJournal of Materials Research and Technology, 2021
Structural, diffuse reflectance spectroscopy, dielectric relaxation processes and electrical conduction mechanism of zirconium (IV) dioxide were investigated.
T. Altalhi   +7 more
doaj   +1 more source

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