Results 61 to 70 of about 9,801 (267)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diffusion to Capture and the Concept of Diffusive Interactions [PDF]

open access: yes, 2019
Diffusion to capture is an ubiquitous phenomenon in many fields in biology and physical chemistry, with implications as diverse as ligand-receptor binding on eukaryotic and bacterial cells, nutrient uptake by colonies of unicellular organisms and the functioning of complex core-shell nanoreactors. Whenever many boundaries compete for the same diffusing
Galanti, Marta   +3 more
openaire   +2 more sources

Diffusion archeology for diffusion progression history reconstruction [PDF]

open access: yesKnowledge and Information Systems, 2014
Diffusion through graphs can be used to model many real-world processes, such as the spread of diseases, social network memes, computer viruses, or water contaminants. Often, a real-world diffusion cannot be directly observed while it is occurring - perhaps it is not noticed until some time has passed, continuous monitoring is too costly, or privacy ...
Emre Sefer, Carl Kingsford
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Evolution of cross-diffusion and self-diffusion

open access: yesJournal of Biological Dynamics, 2009
This article is concerned with the evolution of certain types of density-dependent dispersal strategy in the context of two competing species with identical population dynamics and same random dispersal rates. Such density-dependent movement, often referred to as cross-diffusion and self-diffusion, assumes that the movement rate of each species depends
Yuan, Lou, Salome, Martínez
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ground effect of an inverted double element wing diffuser on a sedan car

open access: yesHeliyon
The diffuser is a critical component in sports cars, enhancing aerodynamics by increasing downforce and reducing drag. Previous studies have focused on its dependence on diffuser incidence, height, and base pressure.
Mustafa Sabeeh Abood, IhsanYahya Hussain
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Thermal Recirculation Modeling for Power Plants in an Estuarine Environment

open access: yesJournal of Marine Science and Engineering, 2017
Many power plants require large quantities of water for cooling purposes. The water taken from the source water body (e.g., lakes, estuaries, bays and rivers) circulates through the plant and returns to the source through outfall with a higher ...
Mehrdad Salehi
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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