Results 91 to 100 of about 2,527,767 (256)
Pulmonary diffusing capacity and capillary blood volume in aging dogs
, 1975 Single-breath carbon monoxide diffusing capacity (DLco), pulmonary capillary blood volume (Vc), and membrane diffusing capacity (Dm) were measured in 24 beagle dogs aged 289–3,882 days. DLco and Vc were a function of age and alveolar volume (Va).
J. R. Gillespie, N. E. Robinson
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Frontiers in MedicineInterstitial lung disease (ILD) is a heterogeneous group of disorders characterized by lung inflammation and fibrosis. Given inconsistent evidence on the prognostic role of body mass index (BMI), we conducted a systematic review and meta-analysis to ...
Yunha Nam +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Association between within breath diffusing capacity (DcoWB), pulmonary blood flow, and workload.
, 2012 Generalized estimating equations were used to create linear regressions representing each association. A: Pulmonary blood flow increase with workload is not significantly different between the flight attendants with abnormal or normal diffusing capacity ...
Thaddeus Haight (172878) +4 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Prediction equations for diffusing capacity (transfer factor) of lung for North Indians
Lung India, 2016 Background: Prediction equations for diffusing capacity of lung for carbon monoxide (DLCO), alveolar volume (VA), and DLCO/VA using the current standardization guidelines are not available for Indian population.
Sunil Kumar Chhabra +2 more
doaj +1 more source
Effect of a systemic A-V fistula and of pulmonary embolization on diffusing capacity
, 1963 Opening an aortic-caval fistula in anesthetized dogs was associated with slight but significant increase of the steady-state diffusing capacity of the lungs.
M. Henry Williams, Bruce J. Sobol
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source