Results 101 to 110 of about 2,527,767 (256)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Measurement of the diffusing capacity of the lung

, 2014
Diese Arbeit beschäftigt sich mit den Grundlagen und Gesetzen der Diffusion sowohl im Allgemeinen als auch in vivo und anschließend werden die Methoden zur Messung der Diffusionskapazität der Lunge beschrieben.
Starzinger, Lisa-Marie
core   +2 more sources

Pulmonary Venous Vasculopathy in Connective Tissue Disease‐Associated Pulmonary Arterial Hypertension With Reduced Diffusion Capacity for Carbon Monoxide

Pulmonary Circulation
Connective tissue disease‐associated pulmonary arterial hypertension (CTD‐PAH) has a poorer prognosis than idiopathic PAH, potentially attributable to pulmonary veno‐occlusive disease (PVOD)‐like involvement.
Shinya Fujisaki, Ryotaro Asano, Hiroyuki Endo, Atsushi Kuraishi, Ryo Takano, Hiroya Hayashi, Keiko Ohta‐Ogo, Kinta Hatakeyama, Kenichi Tsujita, Teruo Noguchi, Takeshi Ogo   +10 more
doaj   +1 more source

Impact of Long COVID on Lung Function in Children

Medeniyet Medical Journal
Objective: While the coronavirus disease-2019 (COVID-19) pandemic has generally resulted in milder illness among children than adults, persistent respiratory symptoms have been increasingly reported in this population. Methods: We conducted a prospective,
Zeynep Reyhan ONAY, Sinem CAN OKSAY, Deniz MAVI TORTOP, Gulay BILGIN, Yetkin AYHAN, Ferit DURANKUS, Saniye GIRIT   +6 more
doaj   +1 more source

Capacity building assistance (CBA) glossary [PDF]

The Capacity Building Assistance (CBA) Glossary has been developed by the Capacity Building Assistance Provider Network (CPN) in partnership with the Capacity Building Branch (CBB), in the Division of HIV/AIDS Prevention (DHAP) at the Centers for Disease

core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Elevated plasma eosinophil-derived neurotoxin is associated with echocardiographic pulmonary vascular involvement in stable COPD

Frontiers in Medicine
BackgroundPulmonary vascular involvement is an important dimension of chronic obstructive pulmonary disease (COPD) heterogeneity, but its biological features may not be fully represented by airflow limitation, gas-transfer impairment, or resting ...
Xiaochen Hu, Fushi Dong, Qi Song, Lu Liu, Shihuan Yu   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Applying a Capacity-Results Framework in Lao PDR and Other Pilot Countries

, 2005
Achieving the Millennium Development Goals (MDG) and poverty reduction objectives of developing countries requires a substantially greater investment in capacity development. This translates into action at three
Hart-Poliquin, Moira, Alameddine, Chirine   +1 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source