Results 121 to 130 of about 2,527,767 (256)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Placental diffusing capacity in unanesthetized rabbits
, 1975 The purpose of this study was to determine the placental diffusing capacity of CO in unanesthetized rabbits. A standard dose of CO was administered to 18 near-term rabbits, and at time intervals varying from 5 min to 4 h maternal and fetal blood samples
TR Bennett, GG Power, E Rocco
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Monaldi Archives for Chest DiseaseLong-term consequences of viral pneumonia on lung function depend on virus-specific tissue injury. Persistent impairment of alveolar-blood gas transport has been described after SARS-CoV-2 pneumonia but has not been investigated following respiratory ...
Roberto W. Dal Negro +2 more
doaj +1 more source
Evaluating the oxygen diffusing capacity of maximally stimulated canine muscle
, 1994 A series of studies over the past several years has been concerned with O2 consumption in the gastrocnemius muscle of the dog. Those experiments indicate that the maximal O2 consumption may be diffusion limited and suggest that such data can be ...
J. L. Gainer
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Association between exercise capacity and airflow and diffusing capacity in pre-ban FAs.
, 2012 The exercise capacity as estimated by maximum oxygen uptake (VO2) was directly associated with (A) FEV1 (r = 0.33; p = 0.002) and with (B) diffusing capacity at rest (r = 0.29; p = 0.008); r: correlation coefficient.
Thaddeus Haight (172878) +4 more
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Lung diffusing capacity: rebreathing method, applicability in nonuniform ventilation
, 1965 We have calculated how the carbon monoxide concentration changes when subjects with different distributions of ventilation and lung diffusing capacity (Dl) respire in a small bag. The curve [loge CO concentration in the bag] versus [time] will sooner or
P. S⊘lvsteen
core +1 more source