Results 201 to 210 of about 2,067,464 (306)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Differentiating lymph node status in malignant melanoma: the role of apparent diffusion coefficient ratio in diffusion-weighted MRI - a prospective diagnostic study. [PDF]

BMC Med Imaging
Kohnen MPE, Mühler M, Arnold A, Lutze S, Busch CJ, Ribback S, Peters K, Kromrey ML, Kirsch M, Gamain J, Mankertz F, Malsch C.   +11 more
europepmc   +1 more source

Acute toxic leucoencephalopathy following protonitazene ingestion

British Journal of Clinical Pharmacology, EarlyView.
Background Distribution of illicit counterfeit alprazolam containing the highly potent synthetic opioid‐receptor agonist protonitazene recently resulted in a number of severe overdoses in Ireland. We report three cases that presented to our hospital, within 6 weeks of one another, following ingestion of illicitly‐sourced alprazolam.
Ruadhan O'Laoi, Holly Acton, Pierce Kavanagh, Isabelle Hunt, Niall Sheehy, Cormac Kennedy   +5 more
wiley   +1 more source

Morphologic and Diffusion-weighted MRI Characteristics of Axillary Lymph Nodes for Predicting Metastasis in Breast Cancer Patients: A Quantitative Analysis. [PDF]

Curr Med Imaging
Sirik M, Poyraz M, Kaplan E.
europepmc   +1 more source

Low‐Field MRI as a Multiparametric Tool for Large Engineered Tissue Characterization

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Advances in 3D bioprinting have enabled the fabrication of large and complex engineered tissues, but their increasing size demands non‐invasive tools for monitoring structure, maturation, and perfusion. Magnetic Resonance Imaging (MRI) offers unique multiparametric capabilities, yet high‐field systems remain costly and inaccessible for most ...
Yilbert Gimenez, Valernst Martial Gilmus, Elliott Cowles, Lucie Essayan, Vincent Semet, Michel Cabrera, Christophe A. Marquette, Simon A. Lambert, Emma Petiot   +8 more
wiley   +1 more source

Can Whole-Body Diffusion-weighted MRI Become a One-Stop-Shop Imaging Modality in Pediatric Sarcoma Imaging? [PDF]

Radiol Imaging Cancer
van Rijn RR, Nievelstein RAJ.
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Deep Learning Reconstruction for ¹²⁹Xe Diffusion-Weighted MRI Enables Use of Natural Abundant Xenon and Improved Image Acceleration. [PDF]

Magn Reson Med
Sundaresan R, Collier GJ, Stewart NJ, Chatterjee S, Venkatesan R, Wolber J, Wild JM.   +6 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Deep Learning Reconstruction of Diffusion-weighted MRI Enables Shorter Examination Times While Maintaining Image Quality in Head and Neck Imaging. [PDF]

Clin Neuroradiol
Almansour H, Brendel JM, Neatu C, Gassenmaier S, Herrmann J, Werner S, Koch V, Darwich O, Weiland E, Benkert T, Altmann S, Kronfeld A, Othman AE, Nikolaou K, Afat S.   +14 more
europepmc   +1 more source