Results 41 to 50 of about 156,789 (313)

Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study. [PDF]

, 2013
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds.
Lawrence, AJ, Barrick, Thomas R., Lawrence Andrew J., Barrick Thomas R., Andrew J Lawrence, Robin G Morris, MacKinnon, Andrew D., Hugh S. Markus, Thomas R Barrick, Bhavini Patel, Robin G. Morris, MacKinnon, AD, Bhavini Patel (405150), Barrick, TR, Philip M. Rich (405153), Markus, HS, Andrew D. MacKinnon, Rich, PM, Thomas R. Barrick (405154), Thomas R. Barrick, Hugh S Markus, Lawrence, Andrew J.; id_orcid, Patel, B, Andrew J. Lawrence, MacKinnon Andrew D., Rich, Philip M., Hugh S. Markus (366687), Andrew J. Lawrence (292444), Robin G. Morris (405151), Morris, RG, Patel Bhavini, Morris Robin G., Morris, Robin G., Andrew D MacKinnon, Rich Philip M., Patel, Bhavini, Philip M Rich, Andrew D. MacKinnon (405152), Markus Hugh S., Philip M. Rich, Markus, Hugh S.   +40 more
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Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Longitudinal measurement of the developing grey matter in preterm subjects using multi-modal MRI.

, 2015
Preterm birth is a major public health concern, with the severity and occurrence of adverse outcome increasing with earlier delivery. Being born preterm disrupts a time of rapid brain development: in addition to volumetric growth, the cortex folds ...
Eaton-Rosen, Zach, Eaton-Rosen, Z, Kendall, Giles S., Alan Bainbridge, Marlow, N, Nicola J. Robertson, Marlow, Neil, Neil Marlow, Ourselin, Sebastien, Modat, Marc, M. Jorge Cardoso, Eliza Orasanu, Modat, M, Robertson, Nicola J., Zach Eaton-Rosen, Robertson, NJ, Melbourne, A, Orasanu, Eliza, Bainbridge, Alan, Melbourne, Andrew, Giles S. Kendall, Sebastien Ourselin, Cardoso, MJ, Ourselin, S, Kendall, GS, Orasanu, E, Bainbridge, A, Andrew Melbourne, Cardoso, M. Jorge, Marc Modat   +29 more
core   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Robertson, Craig A, Robertson, Craig A., William M Holmes, Celestine Santosh, Macrae, I Mhairi, McCabe, Chris, Maria del Rosario Lopez-Gonzalez, Lopez-Gonzalez, Maria del., Barrie Condon, Keith W Muir, Lindsay Gallagher, Holmes, William M., Christopher McCabe, Santosh, Celestine, Craig A Robertson, Lopez-Gonzalez, Maria del Rosario, Holmes, William M, Macrae, I. Mhairi, I Mhairi Macrae, Gallagher, Lindsay, Muir, Keith W, Condon, Barrie, McCabe, Christopher, Muir, Keith W.   +23 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Comparison of diffusion-weighed MRI findings of the testis in patients with the advanced stage unilateral testicular varicocele

Medicine Science, 2017
The aim of this study was to compare the testicular apparent diffusion coefficient (ADC) values of the patients with unilateral advanced stage varicocele and healthy volunteers.
Veysel Burulday, Mehmet Hamdi Sahan, Gulnur Erdem, Ercan Yuvanc   +3 more
doaj   +1 more source

Detection and modeling of non-Gaussian apparent diffusion coefficient profiles in human brain data

, 2002
This work details the observation of non-Gaussian apparent diffusion coefficient (ADC) profiles in multi-direction, diffusion-weighted MR data acquired with easily achievable imaging parameters (b 1000 s/mm2).
BARKER, G. J.; id_orcid, Arridge, S.R., ALEXANDER, D. C., Alexander, D.C., ARRIDGE, S. R., Barker , G.J.   +5 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

The Desmoteplase In Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase [PDF]

, 2005
<p><b>Background and Purpose:</b> Most acute ischemic stroke patients arrive after the 3-hour time window for recombinant tissue plasminogen activator (rtPA) administration.
Fischer, M., Eliasziw, M., Lees, K.R., Kaste, M., Albers, G., Al, R.Y., Hacke, W., Furlan, A., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source