Results 51 to 60 of about 156,789 (313)

Lhermitte-Duclos disease: A case report with radiologic-pathologic correlation

Radiology Case Reports, 2019
Background: Lhermitte-Duclos disease (LDD) stems from the development of a rare benign lesion of uncertain pathogenesis that distorts the normal cerebellar laminar cytoarchitecture.
Chiu-Shih Cheng, MD, Chang-Hsien Ou, MD, Jui-Sheng Chen, MD, Chun-Chung Lui, MD, Lee-Ren Yeh, MD   +4 more
doaj   +1 more source

Diffusion-weighted MRI in head and neck radiology: applications in oncology

, 2011
Extracranial application of diffusion-weighted magnetic resonance imaging (MRI) has gained increasing importance in recent years. As a result of technical advances, this new non-invasive functional technique has also been applied in head and neck ...
Thoeny,
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

DWI in characterization of complex ovarian masses, would it help?

The Egyptian Journal of Radiology and Nuclear Medicine, 2018
Objective: To define the role of diffusion-weighted imaging & apparent diffusion coefficient (ADC) in characterizing complex ovarian masses, with particular concern to differentiating benign versus malignant masses.
Moh Salah Ibrahim Tantawy, Mohamed M. Elrakhawy, Ahmad El-Morsy, Gehad Ahmad Saleh   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Predicting and monitoring cancer treatment response with diffusion-weighted MRI [PDF]

, 2010
An imaging biomarker that would provide for an early quantitative metric of clinical treatment response in cancer patients would provide for a paradigm shift in cancer care. Currently, nonimage based clinical outcome metrics include morphology, clinical,
Thoeny, Harriet C, Ross, Brian D, Thoeny, Harriet C., Harriet C. Thoeny, Brian D. Ross, Ross, Brian D.   +5 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Results of the MRI substudy of the intravenous magnesium efficacy in stroke trial [PDF]

, 2009
<p><b>Background and Purpose:</b>Although magnesium is neuroprotective in animal stroke models, no clinical benefit was confirmed in the Intravenous Magnesium Efficacy in Stroke (IMAGES) trial of acute stroke patients.
Alger, J.R., Lees, K.R., Saver, J.L., Weir, C.J., Starkman, S., Muir, K.W., Davis, S.M., Kidwell, C.S., Chen, C., De Silva, D.A.   +9 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Diffusion-weighted MRI: Role in diagnosing hepatic focal lesions

Journal of Medicine in Scientific Research, 2019
Objective The objective of this study was to highlight the role of quantitative and qualitative diffusion-weighted MRI (DW-MRI) in differentiating benign and malignant hepatic focal lesions, thus increasing the efficacy of conventional hepatic MRI, in ...
Manal A El-Refaei, Mohammed A M. Yousef, Medhat M Refaat, Ibrahim M Helmy   +3 more
doaj   +1 more source