Results 71 to 80 of about 3,559,721 (288)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Diffusion leaky LMS algorithm: Analysis and implementation

open access: yesSignal Processing, 2017
The diffusion least-mean square (dLMS) algorithms have attracted much attention owing to its robustness for distributed estimation problems. However, the performance of such filters may change when they are implemented for suppressing noises from speech signals.
Lu Lu 0005, Haiquan Zhao 0001
openaire   +5 more sources

Improved Mass Diffusion Recommendation Algorithm in Trusted Social Network [PDF]

open access: yesJisuanji gongcheng, 2019
Traditional mass diffusion recommendation algorithm has low diversity and its neglection to user’s social network information and object popularity.Therefore,this paper proposes a mass diffusion recommendation algorithm based on trust mechanism in social
CAI Yongjia,LI Guanyu
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Virtual Network Embedding Algorithm via Diffusion Wavelet

open access: yesIEEE Access, 2019
The great success of the Internet has promoted the development of digital industries and increased the demand for communication bandwidth. For example, ultrahigh-definition videos and vehicle networks require fast bandwidth speed and increase network ...
Lei Zhuang   +5 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Rate Based Synchronous Diffusion Algorithm

open access: yesLatin-American Journal of Computing, 2014
Sensor networks applications often require global time synchronization between numerous sensors. In this paper we implemented the Rate-Based Synchronous Diffusion Algorithm as described in [RE1] on TelosB mote with Contiki.
Danilo Burbano   +3 more
doaj  

Diffusion LMS Based on Message Passing Algorithm

open access: yesIEEE Access, 2019
Diffusion least-mean-square (LMS) is an adaptive algorithm that estimates an unknown global vector from its linear measurements obtained at all nodes in a distributed manner when each node in the network needs to track the unknown vector in real-time ...
Ayano Nakai-Kasai, Kazunori Hayashi
doaj   +1 more source

A Plaintext-Related Dynamical Image Encryption Algorithm Based on Permutation-Combination-Diffusion Architecture

open access: yesIEEE Access, 2020
In this paper, a novel high security plaintext-related dynamical image encryption algorithm is proposed. Compared with the classical permutation-diffusion encryption architecture, we add the combination operation before the diffusion, which uses the 3D ...
Lidong Liu   +3 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

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