DAMARIS – a flexible and open software platform for NMR spectrometer control
Home-built NMR spectrometers with self-written control software have a long tradition in porous media research. Advantages of such spectrometers are not just lower costs but also more flexibility in developing new experiments (while commercial NMR ...
Gädke, Achim +4 more
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ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Adaptive inverse optimal control for unstable reaction-diffusion PDE system [PDF]
summary:We study adaptive inverse optimal boundary control for reaction-diffusion PDE system with unknown coefficient. First, an adaptive boundary control with parameter update rule is designed which no attempt is made to force parameter convergence ...
Cai, Xiushan +5 more
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Astrocytes and diffusive spread of substances in brain extracellular space
Brain function is based on communication between individual cells, neurons and glia. From a traditional point of view, neurons play a central role in the fast transfer of information in the central nervous system while astrocytes, major type of glia ...
Sherpa, Ang D., Hrabetova, Sabina
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Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
[[abstract]]The chorioallantoic membrane (CAM) assays have been intensively used to determine angiogenesis and anti-angiogenesis of medicines. In view of bioactivity, this technique should be performed with kinetic control regime in chicken embryos ...
Hsieh, Chiu-Lan; Peng, Chiung-Chi; Lin, Li-Yun; Cheng, Yu-Ting; Chen, Kuan-Chou; Peng, Robert Y.
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Reaction-Diffusion Systems in the Port-Hamiltonian Framework
Reaction-diffusion systems model the evolution of the constituents distributed in space under the influence of chemical reactions and diffusion. These systems arise naturally in chemistry, but can also be used to model dynamical processes beyond the ...
Scherpen, J.M.A. +3 more
core +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
The role of actor-networks in the diffusion of management accounting innovations: a comparative study of budgetary control, GP method and Activity-Based Costing in France [PDF]
This research is concerned with the diffusion of management accounting innovations viewed as a process of actor-network building and translation. The aim is to better understand the nature of accounting change.
Nicolas Berland +2 more
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