Results 141 to 150 of about 633,726 (317)

Diffusion of Competing Innovations: The Effects of Network Structure on the Provision of Healthcare [PDF]

Medical innovations, in the form of new medication or other clinical practices, evolve and spread through health care systems, impacting on the quality and standards of health care provision, which is demonstrably heterogeneous by geography.
Blanca Gallego, Adam G. Dunn
core  

Intermittent boundary control for robust fixed-time stabilization of uncertain reaction-diffusion systems

Achieving the robust fixed-time stabilization (FxTS) of uncertain reaction-diffusion systems (RDSs) utilizing intermittent boundary control is a valuable and unresolved problem.
Wang, L, Wen, S, Hu, X, Zhu, S, Chen, G
core   +1 more source

Stability and optimal control of two products innovation diffusion system

Results in Control and Optimization
The current study is aimed at analysing a four-compartmental system to examine the interaction and market dissemination of two product categories. In the first category, the product is low-priced and preferred by economically backward people.
Sonu Chugh, Joydip Dhar, Rangan K. Guha
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source

Fast iterative solvers for PDE-constrained optimization problems

, 2013
In this thesis, we develop preconditioned iterative methods for the solution of matrix systems arising from PDE-constrained optimization problems. In order to do this, we exploit saddle point theory, as this is the form of the matrix systems we wish to ...
Pearson, John W
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Pulse‐Level Quantum Robust Control with Diffusion‐Based Reinforcement Learning

Advanced Physics Research
The pulse‐level quantum control presents a large range of external parameter dependencies, including control field noise, frequency detuning, nonlinearities, and uncertainty of Hamiltonian parameters, which can lead to significant deviation from the ...
Yuanjing Zhang, Tao Shang, Chenyi Zhang, Xueyi Guo   +3 more
doaj   +1 more source

Cost-Benefit and Dynamical Investigation of a Fractional-Order Corruption Population Dynamical System

Fractal and Fractional
The main objective of this study was to investigate the effects of control measures on the diffusion of corruption in the population using a fractional order approach with optimal control theory and cost-benefit analysis.
Mehmet Gümüş, Shewafera Wondimagegnhu Teklu   +1 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Industrial Policy and Technology Diffusion: Evidence from Paper Making Machinery in Indonesia [PDF]

technology diffusion ...
Dijk van, M., Szirmai, A.
core