Results 61 to 70 of about 1,065,619 (287)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Diffusion equation for composite materials

Electronic Journal of Differential Equations, 2000
In this article, we study the asymptotic behavior of solutions to the diffusion equation with non-homogeneous Neumann boundary conditions. This equation models a composite material that occupies a perforated domain, in ${mathbb R}^N$, with small holes ...
Mohamed El Hajji
doaj  

On Fuzzy Solutions for Diffusion Equation

Journal of Applied Mathematics, 2015
Our main goal is to define a fuzzy solution for problems involving diffusion. To this end, the solution of fuzzy diffusion-reaction-advection equation will be defined as Zadeh’s extension of deterministic solution of the associated problem.
Jefferson Leite, Moiseis Cecconello, Jackellyne Leite, R. C. Bassanezi   +3 more
doaj   +1 more source

Systematic Investigation of the Physical and Electrochemical Characteristics of the Vanadium (III) Acidic Electrolyte With Different Concentrations and Related Diffusion Kinetics

Frontiers in Chemistry, 2020
Owing to the lack of systematic kinetic theory about the redox reaction of V(III)/V(II), the poor electrochemical performance of the negative process in vanadium flow batteries limits the overall battery performance to a great extent.
Minghua Jing, Minghua Jing, Chengjie Li, Xinyu An, Zeyu Xu, Jianguo Liu, Chuanwei Yan, Dawei Fang, Xinzhuang Fan, Xinzhuang Fan   +9 more
doaj   +1 more source

Effective numerical treatment of sub-diffusion equation with non-smooth solution

, 2018
In this paper we investigate a sub-diffusion equation for simulating the anomalous diffusion phenomenon in real physical environment. Based on an equivalent transformation of the original sub-diffusion equation followed by the use of a smooth operator ...
Li, Yan, Nie, Yufeng, Wang, Jungang, Yang, Zongze   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Retarding Sub- and Accelerating Super-Diffusion Governed by Distributed Order Fractional Diffusion Equations

, 2002
We propose diffusion-like equations with time and space fractional derivatives of the distributed order for the kinetic description of anomalous diffusion and relaxation phenomena, whose diffusion exponent varies with time and which, correspondingly, can
A. Ayache, A. Compte, A. V. Chechkin, A. V. Chechkin, B. J. West, C. Fox, E. Barkai, E. Barkai, E. Lutz, E. W. Montroll, F. Igloi, F. Mainardi, F. Mainardi, G. Zumofen, I. M. Sokolov, I. M. Sokolov, J. Dräger, J. Klafter, J.-P. Bouchaud, K. Diethelm, M. Caputo, M. Caputo, R. Gorenflo, R. Hilfer, R. L. Bagley, R. L. Bagley, R. Metzler, R. Metzler, T. Prosen, Y. G. Sinai   +29 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Low-Complexity Numerical Approach for the Diffusion Equation with Variable Diffusion Coefficient

Mathematics
The diffusion equation models a wide variety of physical and chemical processes and has significant interest in many scientific disciplines. Analytical and numerical methods found in the literature for solving the diffusion equation consider a constant ...
Marta Zárraga-Rodríguez, Patricio Fuentes, Xabier Insausti   +2 more
doaj   +1 more source

Linearized Kompaneetz equation as a relativistic diffusion

, 2009
We show that Kompaneetz equation describing photon diffusion in an environment of an electron gas, when linearized around its equilibrium distribution, coincides with the relativistic diffusion discussed in recent publications.
Dodelson S., Ensslin T. A., Flügge S., Jüttner F., Kompaneetz A. S., Lifshits E. M., Lyubarsky Y. E., Peebles P. J. E., Rybicki G. B., Sunyaev R., Sunyaev R. A., Z. HABA   +11 more
core   +1 more source